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Recombinant interleukin-1ss dilates steelhead trout coronary microvessels: effect of temperature and role of the endothelium, nitric oxide and prostaglandins RESEARCH ARTICLE
Isabel A. S. F. Costa, Travis W. Hein, Christopher J. Secombes, and A. Kurt GamperlInterleukin (IL)-1ß is associated with hypotension and cardiovascular collapse in mammals during heat stroke, and the mRNA expression of this pro-inflammatory cytokine increases dramatically in the blood of Atlantic cod (Gadus morhua, Linnaeus 1758) at high temperatures. These data suggest that IL-1ß release at high temperatures may negatively impact fish cardiovascular function, and be a primary determinant of upper thermal tolerance in this taxa. Thus, we measured the concentration-dependent response of isolated steelhead trout...
Source: Journal of Experimental Biology - May 29, 2015 Category: Biology Authors: Costa, I. A. S. F., Hein, T. W., Secombes, C. J., Gamperl, A. K. Tags: RESEARCH ARTICLE Source Type: research

Recombinant interleukin-1{beta} dilates steelhead trout coronary microvessels: effect of temperature and role of the endothelium, nitric oxide and prostaglandins RESEARCH ARTICLE
Isabel A. S. F. Costa, Travis W. Hein, Christopher J. Secombes, and A. Kurt Gamperl Interleukin (IL)-1β is associated with hypotension and cardiovascular collapse in mammals during heat stroke, and the mRNA expression of this pro-inflammatory cytokine increases dramatically in the blood of Atlantic cod (Gadus morhua) at high temperatures. These data suggest that release of IL-1β at high temperatures negatively impacts fish cardiovascular function and could be a primary determinant of upper thermal tolerance in this taxa. Thus, we measured the concentration-dependent response of isolated steelhead trout (Oncorhync...
Source: Journal of Experimental Biology - July 22, 2015 Category: Biology Authors: Costa, I. A. S. F., Hein, T. W., Secombes, C. J., Gamperl, A. K. Tags: RESEARCH ARTICLE Source Type: research