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Drug: Polyethylene Glycol
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Total 25 results found since Jan 2013.
Titanium dioxide nanoparticles require K < sup > + < /sup > and hydrogen sulfide to regulate nitrogen and carbohydrate metabolism during adaptive response to drought and nickel stress in cucumber
Environ Pollut. 2023 Jun 23:122008. doi: 10.1016/j.envpol.2023.122008. Online ahead of print.ABSTRACTCrop plants face severe yield losses worldwide owing to their exposure to multiple abiotic stresses. The study described here, was conducted to comprehend the response of cucumber seedlings to drought (induced by 15% w/v polyethylene glycol 8000; PEG) and nickel (Ni) stress in presence or absence of titanium dioxide nanoparticle (nTiO2). In addition, it was also investigated how nitrogen (N) and carbohydrate metabolism, as well as the defense system, are affected by endogenous potassium (K+) and hydrogen sulfide (H2S). Cucu...
Source: Environmental Pollution - June 25, 2023 Category: Environmental Health Authors: M Nasir Khan Manzer H Siddiqui Khalaf M Alhussaen Alaa Rafat El-Alosey Meshari Atallah M AlOmrani Hazem M Kalaji Source Type: research
Carbon dots as Reactive Nitrogen Species nanosensors
Anal Chim Acta. 2022 Apr 15;1202:339654. doi: 10.1016/j.aca.2022.339654. Epub 2022 Mar 3.ABSTRACTThree sets of Carbon Dots (Cdots) were produced through the carbohydrates acid thermal decomposition method. These nanoparticles were functionalized with a polymer, known for its biological compatibility: polyethylene glycol, PEG200, and folic acid, FA, a biomolecule associated with the reactive oxygen and nitrogen (ROS/RNS) savaging process, thus resulting CdotsPEG200, CdotsPEG200FA and CdotsFA. These nanoparticles were tested as nitric oxide radical (NO·) sensors and it was determined that CdotsPEG200FA and CdotsFA fluoresce...
Source: Analytica Chimica Acta - March 28, 2022 Category: Chemistry Authors: Marita A Cardoso Abel J Duarte Helena M R Gon çalves Source Type: research
Poly (vinyl alcohol)/chitosan/polyethylene glycol-assembled graphene oxide bio-nanocomposites as a prosperous candidate for biomedical applications and drug/food packaging industry
Int J Biol Macromol. 2022 Jan 17:S0141-8130(22)00100-3. doi: 10.1016/j.ijbiomac.2022.01.086. Online ahead of print.ABSTRACTThe graphene oxide (GO) nanoplates and polyethylene glycol-decorated GO (GO-PEG nano-hybrid) were synthesized and characterized by FTIR, Raman, XRD, AFM, FE-SEM-EDAX and MTT assay. Obtained results confirmed the graphite oxidation and also assembly of PEG upon GO plates. The MTT assay indicated that GO-PEG nanohybrid enhanced biocompatibility to cells compared to the GO. The GO-PEG nanohybrid was introduced to the polyvinyl alcohol/chitosan carbohydrate (PVA/CS) blends. The bio-nanocomposite were prepa...
Source: International Journal of Biological Macromolecules - January 20, 2022 Category: Biochemistry Authors: Saeid Mohammadi Amir Babaei Source Type: research
Osmolytes and crowders regulate aggregation of the cancer-related L106R mutant of the Axin protein
Biophys J. 2021 Jun 1:S0006-3495(21)00453-7. doi: 10.1016/j.bpj.2021.05.024. Online ahead of print.ABSTRACTProtein aggregation is involved in a variety of diseases, including neurodegenerative diseases and cancer. The cellular environment is crowded by a plethora of cosolutes comprising small molecules and biomacromolecules at high concentrations, which may influence the aggregation of proteins in vivo. To account for the effect of cosolutes on cancer-related protein aggregation, we studied their effect on the aggregation of the cancer-related L106R mutant of the Axin protein. Axin is a key player in the Wnt signaling path...
Source: Biophysical Journal - June 4, 2021 Category: Physics Authors: Tommaso Garfagnini Yael Levi-Kalisman Daniel Harries Assaf Friedler Source Type: research
Simultaneous surface functionalization and drug loading: A novel method for fabrication of cellulose nanocrystals-based pH responsive drug delivery system
Int J Biol Macromol. 2021 Jun 1:S0141-8130(21)01176-4. doi: 10.1016/j.ijbiomac.2021.05.193. Online ahead of print.ABSTRACTHerein, a novel strategy for surface functionalization and drug loading of cellulose nanocrystals (CNCs) through formation of hydrazone bonds between functionalized CNCs and aldehyde group containing polyethylene glycol (CHO-PEG)/anticancer drug doxorubicin (DOX) was reported for the first time. DOX could be loaded on PEGylated CNCs with high capacity and released from drug complexes (P-CNCs-D) with pH dependent behavior. The biological evaluation results demonstrated that drug carriers (CNCs-EBO-NH) sh...
Source: International Journal of Biological Macromolecules - June 4, 2021 Category: Biochemistry Authors: Wei Long Hui Ouyang Chaoqun Zhou Weimin Wan Shengxian Yu Kai Qian Meiying Liu Xiaoyong Zhang Yulin Feng Yen Wei Source Type: research
Osmolytes and crowders regulate aggregation of the cancer-related L106R mutant of the Axin protein
Biophys J. 2021 Jun 1:S0006-3495(21)00453-7. doi: 10.1016/j.bpj.2021.05.024. Online ahead of print.ABSTRACTProtein aggregation is involved in a variety of diseases, including neurodegenerative diseases and cancer. The cellular environment is crowded by a plethora of cosolutes comprising small molecules and biomacromolecules at high concentrations, which may influence the aggregation of proteins in vivo. To account for the effect of cosolutes on cancer-related protein aggregation, we studied their effect on the aggregation of the cancer-related L106R mutant of the Axin protein. Axin is a key player in the Wnt signaling path...
Source: Biophysical Journal - June 4, 2021 Category: Physics Authors: Tommaso Garfagnini Yael Levi-Kalisman Daniel Harries Assaf Friedler Source Type: research
Simultaneous surface functionalization and drug loading: A novel method for fabrication of cellulose nanocrystals-based pH responsive drug delivery system
Int J Biol Macromol. 2021 Jun 1:S0141-8130(21)01176-4. doi: 10.1016/j.ijbiomac.2021.05.193. Online ahead of print.ABSTRACTHerein, a novel strategy for surface functionalization and drug loading of cellulose nanocrystals (CNCs) through formation of hydrazone bonds between functionalized CNCs and aldehyde group containing polyethylene glycol (CHO-PEG)/anticancer drug doxorubicin (DOX) was reported for the first time. DOX could be loaded on PEGylated CNCs with high capacity and released from drug complexes (P-CNCs-D) with pH dependent behavior. The biological evaluation results demonstrated that drug carriers (CNCs-EBO-NH) sh...
Source: International Journal of Biological Macromolecules - June 4, 2021 Category: Biochemistry Authors: Wei Long Hui Ouyang Chaoqun Zhou Weimin Wan Shengxian Yu Kai Qian Meiying Liu Xiaoyong Zhang Yulin Feng Yen Wei Source Type: research
Osmolytes and crowders regulate aggregation of the cancer-related L106R mutant of the Axin protein
Biophys J. 2021 Jun 1:S0006-3495(21)00453-7. doi: 10.1016/j.bpj.2021.05.024. Online ahead of print.ABSTRACTProtein aggregation is involved in a variety of diseases, including neurodegenerative diseases and cancer. The cellular environment is crowded by a plethora of cosolutes comprising small molecules and biomacromolecules at high concentrations, which may influence the aggregation of proteins in vivo. To account for the effect of cosolutes on cancer-related protein aggregation, we studied their effect on the aggregation of the cancer-related L106R mutant of the Axin protein. Axin is a key player in the Wnt signaling path...
Source: Biophysical Journal - June 4, 2021 Category: Physics Authors: Tommaso Garfagnini Yael Levi-Kalisman Daniel Harries Assaf Friedler Source Type: research
