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Drug: Morphine
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A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
A synergistic analgesic effect of morphine in combination with the CB1 receptor agonist, ACPA, in normal, hypothyroid, and hyperthyroid male rats
Acta Neurobiol Exp (Wars). 2023;83(2):154-170. doi: 10.55782/ane-2023-014.ABSTRACTBoth cannabinoid and opioid receptors are involved in pain behavior. The administration of morphine and cannabis in rats has been shown to decrease thyroid weight and thyroid‑stimulating hormone (TSH) levels. We hypothesized that the third ventricle, due to its adjacency to the hypothalamus, is involved in the modulation of hypothalamic‑pituitary‑thyroid axis activity and descending pain pathways. The present study examined the effect of intra‑third ventricle administration of morphine and cannabis agents on the modulation of pain beh...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Mohammad-Reza Zarrindast Fatemeh Khakpai Source Type: research
Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice
This study investigated striatal local field potential (LFP) oscillation and locomotor activity following treatments with morphine, a DA release enhancer, and haloperidol (HAL), a DA D2 receptor (D2R) antagonist in mice. After intracranial electrodes were placed into the dorsal striatum of male Swiss albino ICR mice, intraperitoneal injections of morphine or HAL were administered. LFP signals and spontaneous motor activity were recorded simultaneously. The results showed that morphine significantly increased locomotor speed, both low (30.3-44.9 Hz) and high (60.5-95.7 Hz) LFP gamma powers and delta (1-4 Hz)‑gamma (30.3-9...
Source: Acta Neurobiologiae Experimentalis - July 26, 2023 Category: Neurology Authors: Chayaporn Reakkamnuan Dania Cheaha Nifareeda Samerphop Jakkrit Nukitram Ekkasit Kumarnsit Source Type: research
