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Source: Neuro-Oncology
Drug: Morphine

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P05.04 Morphine pretreatment improves the therapeutic efficacy of doxorubicin in an orthotopic model of human glioblastoma
Conclusions:The present findings show that molecules as morphine are able to interfere with molecules normally unable to cross the BBB. This mechanism could be used for new approaches in therapy of refractory CNS tumors as glioblastoma.
Source: Neuro-Oncology - September 20, 2016 Category: Cancer & Oncology Authors: Da Ros, M. Tags: P05 In vitro / in vivo models Source Type: research