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Source: General and Comparative Endocrinology
Drug: Estradiol

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Total 106 results found since Jan 2013.

Seasonal changes in endoplasmic reticulum stress and steroidogenesis in the ovary of the wild ground squirrels (Citellus dauricus Brandt)
Gen Comp Endocrinol. 2023 Aug 19;343:114368. doi: 10.1016/j.ygcen.2023.114368. Online ahead of print.ABSTRACTThe development of the follicle is accompanied by steroidogenesis and secretion, the endoplasmic reticulum (ER) requires significant synthesis of relevant proteins to support changes in the follicular microenvironment. The aim of this study was to investigate whether seasonal changes in gonadotropins and ovarian steroid hormones in the wild ground squirrels induce endoplasmic reticulum stress (ERS) and changes in ERS-mediated unfolded protein response (UPR) signaling. There were significant seasonal differences in o...
Source: General and Comparative Endocrinology - August 21, 2023 Category: Endocrinology Authors: Qingjing Gao Wenjing Lu Sijie Fan Wenqiang Xie Haolin Zhang Yingying Han Qiang Weng Source Type: research

Nesfatin-1 in a Reptile: its role and hormonal regulation in wall lizard testis
Gen Comp Endocrinol. 2023 Jun 20:114337. doi: 10.1016/j.ygcen.2023.114337. Online ahead of print.ABSTRACTNesfatin-1 is a pleiotropic hormone implicated in various physiological functions including reproduction. Studies though limited, have established an important role of the peptide in regulation of testicular functions in mammals and fishes. However, role of nesfatin-1 in regulation of spermatogenesis and testicular steroidogenesis remains completely unexplored in reptiles. Therefore, present study aimed to develop an insight into reproductive phase-dependent testicular expression, function and regulation of nucb2/nesfat...
Source: General and Comparative Endocrinology - June 22, 2023 Category: Endocrinology Authors: Krittika Dotania Mamta Tripathy Umesh Rai Source Type: research

Nesfatin-1 in a reptile: its role and hormonal regulation in wall lizard testis
Gen Comp Endocrinol. 2023 Jun 20;341:114337. doi: 10.1016/j.ygcen.2023.114337. Online ahead of print.ABSTRACTNesfatin-1 is a pleiotropic hormone implicated in various physiological functions including reproduction. Studies though limited, have established an important role of the peptide in regulation of testicular functions in mammals and fishes. However, role of nesfatin-1 in regulation of spermatogenesis and testicular steroidogenesis remains completely unexplored in reptiles. Therefore, present study aimed to develop an insight into reproductive phase-dependent testicular expression, function and regulation of nucb2/ne...
Source: General and Comparative Endocrinology - June 22, 2023 Category: Endocrinology Authors: Krittika Dotania Mamta Tripathy Umesh Rai Source Type: research

Reproductive Cycles of Alligator Snapping Turtles (Macrochelys temminckii)
In this study, we measured monthly plasma sex steroid hormone concentrations of androgen (T+DHT) estradiol-17B (E2), and progesterone (P4), and used ultrasonography to monitor annual reproductive cycles of a captive population of alligator snapping turtles that is maintained under semi-natural conditions in southeastern Oklahoma. Concurrently, we used automated radio telemetry to measure the relative activity levels of male and female alligator snapping turtles and examine these activity patterns in the context of their reproductive cycles. We also measured monthly concentrations of the glucocorticoid (GC) corticosterone (...
Source: General and Comparative Endocrinology - May 27, 2023 Category: Endocrinology Authors: Denise M Thompson Day B Ligon Brian S Edmond S Jane Spangler Brian M Fillmore Kerry G Graves Matthew Lovern Source Type: research

Low estradiol production of non-laying whooping cranes (Grus americana) is associated with the failure of small follicles to enter follicular hierarchy
Gen Comp Endocrinol. 2023 Apr 1:114280. doi: 10.1016/j.ygcen.2023.114280. Online ahead of print.ABSTRACTFor endangered species managed ex situ, production of offspring is a key factor to ensure healthy and self-sustaining populations. However, current breeding goals for the whooping crane (Grus americana) are impeded by poor reproduction. Our study sought to better understand mechanisms regulating ovarian function in ex situ managed whooping cranes and the regulatory function of the hypothalamic-pituitary-gonadal (HPG) axis in relation to follicle formation and egg laying. To characterize hormonal regulation of follicular ...
Source: General and Comparative Endocrinology - April 3, 2023 Category: Endocrinology Authors: Megan E Brown Budhan Pukazhenthi Glenn H Olsen Chris Crowe Warren Lynch David E Wildt Nucharin Songsasen Source Type: research

Synthetic microfiber exposure negatively affects reproductive parameters in male medaka (Oryzias latipes)
In this study, we investigated the changes in HPG axis-related genes in male medaka (Oryzias latipes) exposed to fiber-type microplastics. We confirmed the progression of vitellogenesis, a sign of endocrine disruption, in male fish. In the microfiber-exposed group, microfiber accumulation was confirmed in the gills and intestines. One week after exposure to two different concentrations of microfibers (500 and 1,000 fibers/L), the fish showed increased expression of gonadotropin-releasing hormone (GnRH) and luteinizing hormone receptor (LH-R) mRNA. From day 10 of exposure to the microfibers, there was an increase in the exp...
Source: General and Comparative Endocrinology - January 21, 2023 Category: Endocrinology Authors: Min Ju Kim Jin A Kim Jin Ah Song Kang Hee Kho Cheol Young Choi Source Type: research

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