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Estrogen receptor beta and neural development
Vitam Horm. 2021;116:313-326. doi: 10.1016/bs.vh.2021.02.007. Epub 2021 Mar 9.ABSTRACTThe female sex hormone estradiol (E2, 17β-estradiol) has important functions in the developing brain. In addition to regulating sexual differentiation of the brain, E2 participates in the development of brain areas involved in functions unrelated to reproduction, such as cognition. E2 signals mainly thorough two estrogen receptors; estrogen receptor alpha (ERα) and beta (ERβ). While ERα has distinct functions for sexual imprinting of the developing brain, ERβ is considered to participate in the development of brain areas related to c...
Source: Vitamins and Hormones - March 23, 2021 Category: Endocrinology Authors: Ivan Nalvarte Mukesh Varshney Jose Inzunza Jan- Åke Gustafsson Source Type: research
