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Specialty: Laboratory Medicine
Drug: Metformin

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Total 144 results found since Jan 2013.

Extensive therapeutic effects, underlying molecular mechanisms and disease treatment prediction of Metformin: a systematic review
Transl Res. 2023 Aug 9:S1931-5244(23)00130-5. doi: 10.1016/j.trsl.2023.08.001. Online ahead of print.ABSTRACTMetformin, a first-line management for Type 2 Diabetes Mellitus, has been expansively employed and studied with results indicating its therapeutic potential extending beyond glycaemic control. Beyond its established role, this therapeutic drug demonstrates a broad spectrum of action encompassing over sixty disorders, encompassing metabolic conditions, inflammatory disorders, carcinomas, cardiovascular diseases, and cerebrovascular pathologies. There is clear evidence of metformin's action targeting specific nodes in...
Source: Translational Research : the journal of laboratory and clinical medicine - August 11, 2023 Category: Laboratory Medicine Authors: Yifei Geng Zhen Wang Xiaoyu Xu Xiao Sun Xi Dong Yun Luo Xiaobo Sun Source Type: research

COVID-19 and Early Post-Primary TB: Commonalities of Pathobiology in Pneumonitis and Therapies
CONCLUSION: The commonalities in these pathways suggest that they might be susceptible to adjunctive therapies with metformin and vitamin D3. This is supported by published studies that metformin and vitamin D3 could reduce the severity of both COVID-19 and early post-primary TB infections.PMID:36889761
Source: Annals of Clinical and Laboratory Science - March 8, 2023 Category: Laboratory Medicine Authors: Robert E Brown Robert L Hunter Source Type: research