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Drug: Metformin
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Total 67 results found since Jan 2013.
Presence of nitrosamine impurities in medicinal products
Arh Hig Rada Toksikol. 2021 Mar 30;72(1):1-5. doi: 10.2478/aiht-2021-72-3491. Print 2021 Mar 1.ABSTRACTIn 2018, some sartan medicinal products were reported to be contaminated with nitrosamine compounds, which are potent mutagenic carcinogens. Two nitrosamines received particular attention: N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA). These have since been confirmed in different types of medicinal products, including ranitidine and metformin. Consequently, the European Medicines Agency (EMA) started an investigation into the cause of contamination and an assessment of the risk to patients taking contamin...
Source: Arhiv za Higijenu Rada i Toksikologiju - March 31, 2021 Category: Occupational Health Authors: Ilijana Sedlo Teo Koloni ć Sini ša Tomić Source Type: research
