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Recommendations for the Use of Nonsteroidal Anti-inflammatory Drugs and Cardiovascular Disease Risk: Decades Later, Any New Lessons Learned?
Rheum Dis Clin North Am. 2023 Feb;49(1):179-191. doi: 10.1016/j.rdc.2022.08.006.ABSTRACTNonsteroidal anti-inflammatory drugs (NSAIDs) are among the most prescribed pharmacologic therapies worldwide due to their therapeutic analgesic efficacy and relative tolerability. In the past several decades, various cardiovascular (CV) adverse events have emerged regarding both traditional NSAIDs (tNSAIDs) and cyclo-oxygenase 2 (COX-2) selective (coxibs). This review will provide an updated report on the CV risk profile of NSAIDs, focusing on several of the larger clinical trials, meta-analyses, and registry studies. We aim to provide...
Source: The Medical Clinics of North America - November 24, 2022 Category: General Medicine Authors: Deeba Minhas Anjali Nidhaan M Elaine Husni Source Type: research