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Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species
Toxicol In Vitro. 2023 Feb 8;89:105567. doi: 10.1016/j.tiv.2023.105567. Online ahead of print.ABSTRACTOne of the deadliest types of CNS primary brain cancers is glioblastoma multiforme (GBM), and the survival rate of patients is about 7.2%. The standard treatment for GBM is surgical interventions followed by temozolomide. We investigated for the first time, the cytotoxic impacts of Psidium guajava (P. guajava) on the U87 GBM cell line. We measured cell toxicity through the MTT test following 24 h, 48 h, and 72 h treatment with different concentrations of fruit and seed hydroalcoholic extracts of P. guajava (25-400 μg/ml)....
Source: Toxicology in Vitro - February 9, 2023 Category: Toxicology Authors: Azar Hosseini Mohaddeseh Sadat Alavi Amir Reza Shahraki Arezoo Rajabian Amir Reza Afshari Prashant Kesharwani Amirhossein Sahebkar Source Type: research

Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species (ROS)
Toxicol In Vitro. 2023 Feb 7:105567. doi: 10.1016/j.tiv.2023.105567. Online ahead of print.ABSTRACTOne of the deadliest types of CNS primary brain cancers is glioblastoma multiforme (GBM), and the survival rate of patients is about 7.2%. The standard treatment for GBM is surgical interventions followed by temozolomide. We investigated for the first time, the cytotoxic impacts of Psidium guajava (P. guajava) on the U87 GBM cell line. We measured cell toxicity through the MTT test following 24 h, 48 h, and 72 h treatment with different concentrations of fruit and seed hydroalcoholic extracts of P. guajava (25-400 μg/ml). Li...
Source: Toxicology in Vitro - February 9, 2023 Category: Toxicology Authors: Azar Hosseini Mohaddeseh Sadat Alavi Amir Reza Shahraki Arezoo Rajabian Amir Reza Afshari Prashant Kesharwani Amirhossein Sahebkar Source Type: research

Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species
Toxicol In Vitro. 2023 Feb 8;89:105567. doi: 10.1016/j.tiv.2023.105567. Online ahead of print.ABSTRACTOne of the deadliest types of CNS primary brain cancers is glioblastoma multiforme (GBM), and the survival rate of patients is about 7.2%. The standard treatment for GBM is surgical interventions followed by temozolomide. We investigated for the first time, the cytotoxic impacts of Psidium guajava (P. guajava) on the U87 GBM cell line. We measured cell toxicity through the MTT test following 24 h, 48 h, and 72 h treatment with different concentrations of fruit and seed hydroalcoholic extracts of P. guajava (25-400 μg/ml)....
Source: Toxicology in Vitro - February 9, 2023 Category: Toxicology Authors: Azar Hosseini Mohaddeseh Sadat Alavi Amir Reza Shahraki Arezoo Rajabian Amir Reza Afshari Prashant Kesharwani Amirhossein Sahebkar Source Type: research

Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species (ROS)
Toxicol In Vitro. 2023 Feb 7:105567. doi: 10.1016/j.tiv.2023.105567. Online ahead of print.ABSTRACTOne of the deadliest types of CNS primary brain cancers is glioblastoma multiforme (GBM), and the survival rate of patients is about 7.2%. The standard treatment for GBM is surgical interventions followed by temozolomide. We investigated for the first time, the cytotoxic impacts of Psidium guajava (P. guajava) on the U87 GBM cell line. We measured cell toxicity through the MTT test following 24 h, 48 h, and 72 h treatment with different concentrations of fruit and seed hydroalcoholic extracts of P. guajava (25-400 μg/ml). Li...
Source: Toxicology in Vitro - February 9, 2023 Category: Toxicology Authors: Azar Hosseini Mohaddeseh Sadat Alavi Amir Reza Shahraki Arezoo Rajabian Amir Reza Afshari Prashant Kesharwani Amirhossein Sahebkar Source Type: research

Psidium guajava induces cytotoxicity in human malignant glioblastoma cell line: Role of reactive oxygen species
Toxicol In Vitro. 2023 Feb 8;89:105567. doi: 10.1016/j.tiv.2023.105567. Online ahead of print.ABSTRACTOne of the deadliest types of CNS primary brain cancers is glioblastoma multiforme (GBM), and the survival rate of patients is about 7.2%. The standard treatment for GBM is surgical interventions followed by temozolomide. We investigated for the first time, the cytotoxic impacts of Psidium guajava (P. guajava) on the U87 GBM cell line. We measured cell toxicity through the MTT test following 24 h, 48 h, and 72 h treatment with different concentrations of fruit and seed hydroalcoholic extracts of P. guajava (25-400 μg/ml)....
Source: Toxicology in Vitro - February 9, 2023 Category: Toxicology Authors: Azar Hosseini Mohaddeseh Sadat Alavi Amir Reza Shahraki Arezoo Rajabian Amir Reza Afshari Prashant Kesharwani Amirhossein Sahebkar Source Type: research