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Drug: Gleevec
Nutrition: Antidoxidants
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Total 5 results found since Jan 2013.
Neuroprotective effects of an < em > in vitro < /em > BBB permeable phenoxythiophene sulfonamide small molecule in glutamate-induced oxidative injury
Exp Ther Med. 2022 Jan;23(1):79. doi: 10.3892/etm.2021.11002. Epub 2021 Nov 25.ABSTRACTReactive oxygen species (ROS) play a central role in oxidative stress-associated neuronal cell death during ischemia. Further investigation into the inhibition of excessive ROS generation post-stroke is urgently required for the treatment of ischemic stroke. In the present study, the neuroprotective properties of the blood-brain barrier (BBB) penetrant B355227 were investigated. B355227 is a chemical analogue of B355252, and the role of the phenoxythiophene sulfonamide compound B355227 was further investigated in a glutamate-induced oxid...
Source: Experimental and Therapeutic Medicine - December 23, 2021 Category: General Medicine Authors: Smritee Pokharel Nailya S Gliyazova Srinivasa R Dandepally Alfred L Williams Gordon C Ibeanu Source Type: research
