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Drug: Medroxyprogesterone
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Incidence of herpes simplex virus type 2 infection among African women using depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception: a nested randomized trial
Clin Infect Dis. 2021 Dec 15:ciab1027. doi: 10.1093/cid/ciab1027. Online ahead of print.ABSTRACTBACKGROUND: Globally, women have higher herpes simplex type 2 (HSV-2) prevalence than men; data from observational studies suggest a possible association of HSV-2 acquisition with use of intramuscular depot medroxyprogesterone acetate (DMPA-IM).METHODS: Within a randomized trial of the effect of three contraceptive methods - DMPA-IM, a copper intrauterine device (IUD), and a levonorgestrel (LNG) implant - on HIV acquisition, we assessed HSV-2 acquisition. HSV-2 and HIV seronegative women, aged 16-35 years, and seeking effective ...
Source: Herpes - December 15, 2021 Category: Infectious Diseases Authors: Nelly R Mugo Randy M Stalter Renee Heffron Helen Rees Caitlin W Scoville Charles Morrison Athena P Kourtis Elizabeth Bukusi Mags Beksinka Neena M Philip Ivana Beesham Jen Deese Vinodh Edward Deborah Donnell Jared M Baeten Evidence for Contraceptive Option Source Type: research
