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Multidimensional analysis of sedentary behaviour and participation in Spanish stroke survivors (Part&Sed-Stroke): a protocol for a longitudinal multicentre study
Introduction Stroke survivors usually experience long-lasting functional, emotional and social consequences that might contribute to sedentary behaviour and participation restrictions, which are important targets to address during rehabilitation. However, the trajectory and inter-relationship between these factors are unknown. Methods and analysis Part&Sed is a research project based on an observational study design with 6 and 12 months of follow-ups in stroke survivors. In addition, a qualitative analysis of the impact of the stroke on the stroke survivor, validation of the Satisfaction with Daily Occupation-Occupati...
Source: BMJ Open - February 15, 2023 Category: General Medicine Authors: de Diego-Alonso, C., Alegre-Ayala, J., Buesa, A., Blasco-Abadia, J., Lopez-Royo, M. P., Roldan-Perez, P., Giner-Nicolas, R., Part&Sed-Stroke Collaborators Group, Gu&x0308;eita-Rodriguez, J., Fini, N. A., Domenech-Garcia, V., Bellosta-Lopez, P., Navarro, L Tags: Open access, Neurology Source Type: research

Allogeneic adipose tissue-derived mesenchymal stem cells in ischaemic stroke (AMASCIS-02): a phase IIb, multicentre, double-blind, placebo-controlled clinical trial protocol
Introduction Stroke is a serious public health problem, given it is a major cause of disability worldwide despite the spread of recanalisation therapies. Enhancement of brain plasticity with stem cell administration is a promising innovative therapy to reduce sequelae in these patients. Methods and analysis We have developed a phase IIb, multicentre, randomised, double-blind, placebo-controlled clinical trial protocol to evaluate the safety and efficacy of intravenous administration of allogeneic adipose tissue-derived mesenchymal stem cells (AD-MSCs) in patients with acute ischaemic stroke, concurrently with conventional...
Source: BMJ Open - August 9, 2021 Category: General Medicine Authors: de Celis-Ruiz, E., Fuentes, B., Moniche, F., Montaner, J., Borobia, A. M., Gutierrez-Fernandez, M., Diez-Tejedor, E. Tags: Open access, Neurology Source Type: research

The economic burden of stroke: a systematic review of cost of illness studies
J Med Life. 2021 Sep-Oct;14(5):606-619. doi: 10.25122/jml-2021-0361.ABSTRACTStroke is one of the leading causes of morbidity and mortality worldwide. As the number of stroke cases is rising from one year to another, policymakers require data on the amount spent on stroke to enforce better financing policies for prevention, hospital care, outpatient rehabilitation services and social services. We aimed to systematically assess the economic burden of stroke at global level. Cost of stroke studies were retrieved from five databases. We retrieved the average cost per patient, where specified, or estimated it using a top-down a...
Source: Journal of Medicine and Life - January 14, 2022 Category: General Medicine Authors: Stefan Strilciuc Diana Alecsandra Grad Constantin Radu Diana Chira Adina Stan Marius Ungureanu Adrian Gheorghe Fior-Dafin Muresanu Source Type: research

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