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Cardiac Troponin T and creatine kinase MB fraction levels among patients with acute ischemic stroke in Nigeria
Conclusion: The mean values of serum cTnT and CK-MB were higher in acute ischaemic stroke patients compared to controls. Serum cardiac Troponin t level may be a significant biomarker of the severity of stroke.
Source: Nigerian Journal of Clinical Practice - January 29, 2018 Category: Rural Health Authors: HM Suleiman IS Aliyu SA Abubakar MS Isa JM El-Bashir R Adamu MZ Ibrahim A Mohammed R Yusuf M Manu AB Dogara SK Mustapha N Bello SA Ozovehe Source Type: research

Stroke risk factors among participants of a world stroke day awareness program in South-Western Nigeria
Conclusion: Stroke risk factors such as hypertension and obesity were common among the participants of the world stroke day awareness program in an urban area of Nigeria. Community screening and modification of these risk factors should be intensified in order to reduce stroke morbidity and mortality.
Source: Nigerian Journal of Clinical Practice - August 20, 2015 Category: Rural Health Authors: MA KomolafeMOB OlaoguAM AdebiyiAO ObembeMB FawaleAA Adebowale Source Type: research

Relation between index of cardioelectrophysiological balance and stroke severity in patients with acute ischemic stroke
Conclusion: Our results suggested that iCEB is associated with stroke severity on admission in patients with acute ischemic stroke. It is known that high iCEB is associated with torsade de pointes (TdP), ventricular tachycardia.
Source: Nigerian Journal of Clinical Practice - June 10, 2020 Category: Rural Health Authors: U Ozturk O Ozturk Source Type: research

Awareness of risk factors and warning signs of stroke among nursing students: Results from questionnaire
Conclusion: Students had a good knowledge of some of the warning signs and risk factors about stroke. Therefore, it is recommended that this subject should be emphasized more in course contents.
Source: Nigerian Journal of Clinical Practice - May 20, 2021 Category: Rural Health Authors: H Kankaya O Usta Yesilbalkan Source Type: research

The effect of emotional distress on functional outcomes in acute stroke patients
Conclusion: The results of the study showed that acute stroke patients with a good emotional state had better functional outcomes. It can be concluded that evaluating the emotional state and existing problems while planning of rehabilitation programs will make a positive contribution to both the functional and emotional states of acute stroke patients.
Source: Nigerian Journal of Clinical Practice - November 12, 2019 Category: Rural Health Authors: A Gunal F Baskurt Z Baskurt Source Type: research

Changes in stroke volume variation and cardiac index during open major bowel surgery
Conclusion: SVV, a dynamic index of fluid responsiveness can be used to monitor patients expected to have large fluid shifts during major abdominal surgery. It is very specific and has a high negative predictive value. When SVV increases, CI is usually maintained. Since many factors affect SVV and CI, any increase in SVV >13%, must be correlated with other parameters before administration of the fluid challenge.
Source: Nigerian Journal of Clinical Practice - November 15, 2021 Category: Rural Health Authors: SP Prabhu A Nileshwar HM Krishna M Prabhu Source Type: research

Hemoglobin A1c-related histologic characteristics of symptomatic carotid plaques
Conclusions: Increased HbA1c values seem to contribute to plaque instability through the formation of a thin fibrous cup. Thus, of the carotid artery plaque parameters including fibrous cup thickness, plaque rupture, lipid core, inflammation, intraplaque hemorrhage, thrombus, calcification, necrotic core, and neovascularization, fibrous cup thickness is the only histomorphological feature that affected by HbA1c.
Source: Nigerian Journal of Clinical Practice - March 5, 2019 Category: Rural Health Authors: M Tecellioglu S Alan S Kamisli FS Tecellioglu O Kamisli C Ozcan Source Type: research

The neuroprotection effect of oxygen therapy: A systematic review and meta-analysis
This study reviews the oxygen therapy (normobaric oxygen [NBO] and hyperbaric oxygen [HBO]) in both stroke and traumatic brain injury (TBI) patients and meta-analyzes the efficacy of two oxygen therapies in different kinds of injuries. In stroke patients, NBO showed significant improvement in reperfusion rate while there is no favorable outcome effect of HBO treatment. In patients with TBI, HBO showed significant improvement of Glasgow outcome scale score and reduction of overall mortality while NBO may play a favorable role in improving brain metabolism.
Source: Nigerian Journal of Clinical Practice - April 2, 2018 Category: Rural Health Authors: Z Deng W Chen J Jin J Zhao H Xu Source Type: research

The distribution and pattern of neurological disease in a neurology clinic in Ile-Ife, Nigeria
Conclusion: Epilepsy and stroke are the commonest neurological disorders in the outpatient setting and there should be more studies in the community on their prevalence and impact.
Source: Nigerian Journal of Clinical Practice - November 12, 2018 Category: Rural Health Authors: MA Komolafe OF Owagbemi TI Alimi Source Type: research

Marfan Syndrome with Aortic Root Disease, Severe Heart Failure and Aortic Dissection- Two Case Reports
PO Njoku, NC Mbadiwe, BJ Onwubere, EC Ejim, BC Anisiuba, TC Iyidobi, CT OnyemaNigerian Journal of Clinical Practice 2022 25(2):205-210 Marfan syndrome is an uncommon inheritable connective tissue disease which affects the cardiovascular system. This paper presents two cases of Marfan Syndrome with predominant aortic root disease that were seen at the Cardiology Clinic of University of Nigeria Teaching Hospital, Enugu, Nigeria. Their biography, clinical features and echocardiography parameters were captured using structured questionnaire. Both were young males in their 4th decade of life, and had advanced aortic root disea...
Source: Nigerian Journal of Clinical Practice - February 16, 2022 Category: Rural Health Authors: PO Njoku NC Mbadiwe BJ Onwubere EC Ejim BC Anisiuba TC Iyidobi CT Onyema Source Type: research

Is it possible to predict the outcome of endovascular thrombectomy for hyperdense middle cerebral artery sign at the time of first admission ?
Conclusion: We showed that the presence of HMCAS in initial CT was not helpful in predicting good clinical outcomes in patients undergoing endovascular therapy patients. However, the presence of HMCAS is related to more new territory embolism during the procedure. Different endovascular strategies may be applied to these patients.
Source: Nigerian Journal of Clinical Practice - October 26, 2022 Category: Rural Health Authors: O Aykac AO Ozdemir U Cenikli Source Type: research

Knowledge of medical students about epilepsy: Need for a change
Conclusion: The content of medical curriculum in Africa should emphasize not only the content of lectures on epilepsy but also the need for students to go through neurology posting during their training. The outcome would be both better knowledge and improved physician–patient relations.
Source: Nigerian Journal of Clinical Practice - August 8, 2017 Category: Rural Health Authors: BA Ezeala-Adikaibe T Okpara OS Ekenze O Onodugo NP Ezeala-Adikaibe T Nnaji G Onyebueke Source Type: research

Doppler sonographic evaluation of venogenic extremity swellings: Analysis of 170 patients from Kano, Nigeria
Conclusion: There was a predominance of females and femoro-popliteal segments in DVT. Doppler ultrasound is very useful in the evaluation of extremity DVT. All clinically suspected cases should be evaluated with this modality due to limited sensitivity of clinical evaluation in the diagnosis of DVT. Further correlative studies in comparison to venography and hematologic indices are also recommended.
Source: Nigerian Journal of Clinical Practice - September 11, 2017 Category: Rural Health Authors: A Ismail AM Tabari K Isyaku Source Type: research

The Pattern of significant lesions found in computerized tomography scan of recurrent seizure patients at a center in Enugu, Nigeria
Conclusion: Computed tomography scan has a high diagnostic yield, especially in elderly patients with recurrent generalized seizures. Brain tumors, encephalomalacia, and HCP are most common causes of recurrent seizures in the adults.
Source: Nigerian Journal of Clinical Practice - December 1, 2017 Category: Rural Health Authors: AB Ezeala-Adikaibe SC Ohaegbulam CA Ndubuisi Source Type: research

The relationship between plasma homocysteine levels and MTHFR gene variation, age, and sex in Northeast China
Conclusion: High plasma homocysteine levels were linked to the MTHFR gene mutation. In addition, plasma homocysteine levels increased significantly with age with male's homocysteine levels higher than that of females.
Source: Nigerian Journal of Clinical Practice - March 5, 2019 Category: Rural Health Authors: F Wang X Sui N Xu J Yang H Zhao X Fei Z Zhang Z Luo Y Xin B Qin X Zhao S Cao Y Zhang Z Yang Source Type: research

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