Hemoglobin A1c-related histologic characteristics of symptomatic carotid plaques
Conclusions: Increased HbA1c values seem to contribute to plaque instability through the formation of a thin fibrous cup. Thus, of the carotid artery plaque parameters including fibrous cup thickness, plaque rupture, lipid core, inflammation, intraplaque hemorrhage, thrombus, calcification, necrotic core, and neovascularization, fibrous cup thickness is the only histomorphological feature that affected by HbA1c.
PCSK9 inhibitor alirocumab lowered LDL cholesterol by 35% over placebo in ODYSSEY HoFH, the largest ever randomized lipid-lowering trial in homozygous familial hypercholesterolemia.Medscape Medical News
In the first description of an'end-stage renal disease belt', authors note an increased burden on the kidney donor system.Medscape Medical News
Second Sight Medical Products is the latest medtech company to face tough losses as a result of the financial impact of the novel coronavirus (SARS-CoV-2). The Sylmar, CA-based company is laying off 84 of its 108 employees and said it intends to wind-down operations. The firm develops implantable visual prosthetics that are intended to create an artificial form of useful vision for blind individuals. FDA greenlit the Argus II retinal prosthesis system in 2013. Plans now call for the Second Sight to retain an adviser experienced in winding down operations to guide the board on the next steps. Any wind down activity, if impl...
HIGH blood pressure means a person's blood pressure is consistently too high and dangerous consequences could ensue. With many on lock down and self-isolating, how can you properly measure your blood pressure without the equipment?
Most transgender adults seeking gender-affirming surgery (GAS) experienced gender dysphoria by age 7, a cross-sectional study at Cedars-Sinai Medical Center in Los Angeles suggests.Reuters Health Information
Publication date: Available online 31 March 2020Source: Diabetes &Metabolic Syndrome: Clinical Research &ReviewsAuthor(s): Andrea Da Porto, Viviana Casarsa, Gianluca Colussi, Cristiana Catena, Alessandro Cavarape, Leonardo Sechi
Publication date: April 2020Source: Canadian Journal of Diabetes, Volume 44, Issue 3Author(s): Ilia Ostrovski, Leif E. Lovblom, Daniel Scarr, Alanna Weisman, Nancy Cardinez, Andrej Orszag, C. Marcelo Falappa, Émilie D'Aoust, Ahmad Haidar, Rémi Rabasa-Lhoret, Laurent Legault, Bruce A. Perkins
Emilio Rodríguez-Castro1,2, Manuel Rodríguez-Yáñez1,2, Susana Arias1,2, María Santamaría1,2, Iria López-Dequidt1,2, Ignacio López-Loureiro1, Manuel Rodríguez-Pérez1, Pablo Hervella1, Tomás Sobrino1, Francisco Campos1, José Castillo1* and Ramón Iglesias-Rey1* 1Clinical Neurosciences Research Laboratory, Department of Neurology, Clinical University Hospital, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, Spain2Stroke Unit, Department of Neurology, Hospital Clínico Universitario, Santiago...
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this techniqu...
Conclusion: We found an independent association between FXII levels and the risk of hemorrhagic stroke, but not between FXII levels and ischemic stroke or myocardial infarction.Cerebrovasc Dis Extra 2017;7:84 –94