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Vaccination: Veterinary Vaccinations
Countries: New Zealand Health
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Total 73 results found since Jan 2013.
Preclinical safety assessment of the suction-assisted intradermal injection of the SARS-CoV-2 DNA vaccine candidate pGO-1002 in white rabbit
Arch Toxicol. 2023 Jan 23:1-13. doi: 10.1007/s00204-023-03446-y. Online ahead of print.ABSTRACTpGO-1002, a non-viral DNA vaccine that expresses both spike and ORF3a antigens of SARS-CoV-2, is undergoing phase 1 and phase 2a clinical trials in Korea and the US. A preclinical repeated-dose toxicity study in New Zealand white rabbits in compliance with Good Laboratory Practice (GLP) was conducted to assess the potential toxicity, local tolerance, and immunogenicity of the vaccine and GeneDerm suction device. The dose rate was 1.2 mg/head pGO-1002, and this was administered intradermally to a group of animals (eight animals/se...
Source: Archives of Toxicology - January 22, 2023 Category: Toxicology Authors: Seunghee Oh Min Seong Jang Kyung Jin Jung Ji-Seok Han Hyojin Lee Areum Gil Bohyun Jeon Christine C Roberts Joel N Maslow Yong-Bum Kim Kang-Hyun Han Source Type: research
Biotechnological Based Recombinant Protein Vaccines Developed Against Toxoplasmosis
Turkiye Parazitol Derg. 2022 Nov 28;46(4):342-357. doi: 10.4274/tpd.galenos.2022.41636.ABSTRACTToxoplasma gondii (T. gondii) that can infect most warm-blooded animals and humans, is an obligate intracellular apicomplexan parasite with a wide host range. About one-third of the world's population is infected with this parasite. While toxoplasmosis progresses asymptomatically in individuals with a strong immune system, it can cause serious clinical manifestations and death in immunocompromised individuals. The parasite is transmitted to humans through the consumption of water and food contaminated with cat feces, as well as r...
Source: Turkish Society for Parasitology - November 29, 2022 Category: Parasitology Authors: Tu ğba Karakavuk Ceren G ül Muhammet Karakavuk Ayt ül Gül Sedef Erkunt Alak H üseyin Can Cemal Ün Mert D öşkaya Adnan Y üksel Gürüz Aysu De ğirmenci Döşkaya Source Type: research
