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Molecules, Vol. 28, Pages 6547: Antioxidant and Antibacterial Activity of Mexican Oregano Essential Oil, Extracted from Plants Occurring Naturally in Semiarid Areas and Cultivated in the Field and Greenhouse in Northern Mexico
The objective was to compare the antioxidant and antibacterial activity of Mexican oregano essential oil obtained from plants occurring naturally in semiarid areas (Wild1 and Wild2), and those cultivated in the field (CField) and greenhouse (CGreenhouse) in northern Mexico. The Mexican oregano essential oil extraction was performed using the hydrodistillation method, the antioxidant activity was determined using the ABTS method, and the antibacterial activity was assessed through bioassays under the microwell method at nine different concentrations. The aim was to determine the diameter of the inhibition zone and, conseque...
Source: Molecules - September 9, 2023 Category: Chemistry Authors: Ruben I. Marin-Tinoco Angie Tatiana Ortega-Ram írez Maricela Esteban-Mendez Oscar Silva-Marrufo Laura E. Barragan-Ledesma Luis M. Valenzuela-N úñez Edwin A. Brice ño-Contreras Maria A. Sari ñana-Navarrete Abelardo Camacho-Luis Cayetano Navarrete-Moli Tags: Article Source Type: research

Molecules, Vol. 27, Pages 5714: A Branched and Double Alpha-Gal-Bearing Synthetic Neoglycoprotein as a Biomarker for Chagas Disease
onica Suarez Douglas M. Watts Iliana R. Malo Janine M. Ramsey Belkisyolé Alarcón De Noya Oscar Noya Igor C. Almeida Katja Michael Chagas disease (CD) is caused by the parasite Trypanosoma cruzi and affects 6–7 million people worldwide. The diagnosis is still challenging, due to extensive parasite diversity encompassing seven genotypes (TcI-VI and Tcbat) with diverse ecoepidemiological, biological, and pathological traits. Chemotherapeutic intervention is usually effective but associated with severe adverse events. The development of safer, more effective therapies is hampered by the lack o...
Source: Molecules - September 5, 2022 Category: Chemistry Authors: Alba L. Montoya Elisa G. Carvajal Uriel Ortega-Rodriguez Igor L. Estevao Roger A. Ashmus Sohan R. Jankuru Susana Portillo Cameron C. Ellis Colin D. Knight Julio Alonso-Padilla Luis Izquierdo Maria-Jesus Pinazo Joaquim Gascon Veronica Suarez Douglas M. Wat Tags: Article Source Type: research

Molecules, Vol. 27, Pages 5393: Phytochemical Compounds and Pharmacological Properties of Larrea tridentata
goza-Bastida For centuries, traditional medicine from plants (phytotherapy) was the only treatment for infectious and non-infectious diseases. Although it is still practiced in several countries with excellent therapeutic results, it is frequently underestimated because, unlike Western medicine, it is not based on an empirical scientific foundation. However, interest in the search for plant-based therapeutic resources has been stimulated by disciplines such as phytochemistry and the side effects of conventional pharmacological therapies. For example, Larrea tridentata is a perennial shrub used in traditional medicine i...
Source: Molecules - August 24, 2022 Category: Chemistry Authors: Ana Lizet Morales-Ubaldo Nallely Rivero-Perez Benjam ín Valladares-Carranza Alfredo Madariaga-Navarrete Rosa Isabel Higuera-Piedrahita Luc ía Delgadillo-Ruiz R ómulo Bañuelos-Valenzuela Adrian Zaragoza-Bastida Tags: Review Source Type: research

Molecules, Vol. 27, Pages 1244: Chitosan Sensitivity of Fungi Isolated from Mango (Mangifera indica L.) with Anthracnose
a-Obregón In Mexico, the mango crop is affected by anthracnose caused by Colletotrichum species. In the search for environmentally friendly fungicides, chitosan has shown antifungal activity. Therefore, fungal isolates were obtained from plant tissue with anthracnose symptoms from the state of Guerrero in Mexico and identified with the ITS and β-Tub2 genetic markers. Isolates of the Colletotrichum gloeosporioides complex were again identified with the markers ITS, Act, β-Tub2, GADPH, CHS-1, CaM, and ApMat. Commercial chitosan (Aldrich, lot # STBF3282V) was characterized, and its antifungal ac...
Source: Molecules - February 12, 2022 Category: Chemistry Authors: Griselda Valenzuela-Ortiz Soila Maribel Gaxiola-Camacho Cesar San-Mart ín-Hernández Miguel Ángel Martínez-Téllez Emmanuel Aispuro-Hern ández Jaime Lizardi-Mendoza Eber Add í Quintana-Obregón Tags: Article Source Type: research

Molecules, Vol. 26, Pages 7632: Lamiaceae in Mexican Species, a Great but Scarcely Explored Source of Secondary Metabolites with Potential Pharmacological Effects in Pain Relief
Pellicer The search for molecules that contribute to the relief of pain is a field of research in constant development. Lamiaceae is one of the most recognized families world-wide for its use in traditional medicine to treat diseases that include pain and inflammation. Mexico can be considered one of the most important centers of diversification, and due to the high endemism of this family, it is crucial for the in situ conservation of this family. Information about the most common genera and species found in this country and their uses in folk medicine are scarcely reported in the literature. After an extensive inspe...
Source: Molecules - December 16, 2021 Category: Chemistry Authors: Alberto Hernandez-Leon Gabriel Fernando Moreno-P érez Martha Mart ínez-Gordillo Eva Aguirre-Hern ández Mar ía Guadalupe Valle-Dorado Mar ía Irene Díaz-Reval Mar ía Eva González-Trujano Francisco Pellicer Tags: Review Source Type: research

Molecules, Vol. 26, Pages 4225: Synthesis and Insecticidal Evaluation of Chiral Neonicotinoids Analogs: The Laurel Wilt Case
o Ramón E. Díaz de León-Gómez José L. Olivares-Romero Xyleborus sp beetles are types of ambrosia beetles invasive to the United States and recently also to Mexico. The beetle can carry a fungus responsible for the Laurel Wilt, a vascular lethal disease that can host over 300 tree species, including redbay and avocado. This problem has a great economic and environmental impact. Indeed, synthetic chemists have recently attempted to develop new neonicotinoids. This is also due to severe drug resistance to “classic” insecticides. In this research, a series of neonicotinoids analogs were synthesized, characteri...
Source: Molecules - July 12, 2021 Category: Chemistry Authors: Sa úl A. Luna-Hernández Israel Bonilla-Landa Alfonso Reyes-Luna Alfredo Rodr íguez-Hernández Ulises Cuapio-Mu ñoz Luis A. Ibarra-Ju árez Gabriel Suarez-Mendez Felipe Barrera-M éndez Irving D. P érez-Landa Francisco J. Enr íquez-Medrano Ram ón E. Tags: Article Source Type: research

Molecules, Vol. 26, Pages 4178: Cytotoxicity of a Lipid-Rich Extract from Native Mexican Avocado Seed (Persea americana var. drymifolia) on Canine Osteosarcoma D-17 Cells and Synergistic Activity with Cytostatic Drugs
In conclusion, avocado could be a potential source of bioactive molecules in the searching treatments for osteosarcoma.
Source: Molecules - July 9, 2021 Category: Chemistry Authors: Salvador Padilla-Arellanes Rafael Salgado-Garciglia Marisol B áez-Magaña Alejandra Ochoa-Zarzosa Joel Edmundo L ópez-Meza Tags: Article Source Type: research

Molecules, Vol. 24, Pages 897: Insecticidal and Nematicidal Contributions of Mexican Flora in the Search for Safer Biopesticides
lo Plant metabolites have been used for many years to control pests in animals and to protect crops. Here, we reviewed the available literature, looking for the species of Mexican flora for which extracts and metabolites have shown activity against pest insects and parasitic nematodes of agricultural importance, as well as against nematodes that parasitize domestic cattle. From 1996 to 2018, the search for novel and eco-friendly biopesticides has resulted in the identification of 114 species belonging to 36 botanical families of Mexican plants with reported biological effects on 20 insect species and seven nematode spe...
Source: Molecules - March 3, 2019 Category: Chemistry Authors: Beatriz Hern ández-Carlos Marcela Gamboa-Angulo Tags: Review Source Type: research