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Total 18 results found since Jan 2013.

Matching-Adjusted Indirect Treatment Comparison to Assess the Comparative Efficacy of Ciltacabtagene Autoleucel in CARTITUDE-1 Versus Belantamab Mafodotin in DREAMM-2, Selinexor-Dexamethasone in STORM Part 2, and Melphalan Flufenamide-Dexamethasone in HORIZON for the Treatment of Patients With Triple-Class Exposed Relapsed or Refractory Multiple Myeloma
CONCLUSION: Cilta-cel showed improved efficacy over each comparator for all outcomes, demonstrating its potential as an efficacious treatment for patients with triple-class exposed RRMM.PMID:35764490 | DOI:10.1016/j.clml.2022.04.025
Source: Clinical Lymphoma and Myeloma - June 28, 2022 Category: Cancer & Oncology Authors: Katja Weisel Amrita Krishnan Jordan M Schecter Martin Vogel Carolyn C Jackson William Deraedt Tzu-Min Yeh Arnob Banerjee Fevzi Yalniz Tonia Nesheiwat Suzy Van Sanden Joris Diels Satish Valluri Saad Z Usmani Jesus G Berdeja Sundar Jagannath Tom Martin Source Type: research

Netupitant-Palonosetron (NEPA) in Preventing Chemotherapy-Induced Nausea and Vomiting: From Clinical Trials to Daily Practice
Curr Cancer Drug Targets. 2022 May 13. doi: 10.2174/1568009622666220513094352. Online ahead of print.ABSTRACTChemotherapy-induced nausea and vomiting (CINV) is a common adverse event associated with many anticancer therapies and can negatively impact patients' quality of life and potentially limit the effectiveness of chemotherapy. Currently, CINV can be prevented in most patients with guideline-recommended antiemetic regimens. However, clinicians do not always follow guidelines, and patients often face difficulties adhering to their prescribed treatments. Therefore, approaches to increase guideline adherence need to be im...
Source: Current Cancer Drug Targets - May 16, 2022 Category: Cancer & Oncology Authors: Matti Aapro Karin Jordan Florian Scott é Luigi Celio Meinolf Karthaus Eric Roeland Source Type: research

The Prevention and Treatment of Nausea and Vomiting During Tumor Therapy
CONCLUSION: Detailed, effective, risk profile-adapted algorithms for the prevention and treatment of nausea and vomiting are now available for patients undergoing classic chemotherapy regimens or combined radiotherapy and chemotherapy. Optimal symptom control for patients undergoing oral tumor therapy over multiple days in the outpatient setting remains a challenge.PMID:35140010 | DOI:10.3238/arztebl.m2022.0093
Source: Deutsches Arzteblatt International - February 10, 2022 Category: General Medicine Authors: Franziska Jahn Bernhard W örmann Juliane Brandt Annette Freidank Petra Feyer Karin Jordan Source Type: research

Effects-based monitoring of bioactive compounds associated with municipal wastewater treatment plant effluent discharge to the South Platte River, Colorado, USA
Environ Pollut. 2021 Aug 6;289:117928. doi: 10.1016/j.envpol.2021.117928. Online ahead of print.ABSTRACTPrevious studies have detected numerous organic contaminants and in vitro bioactivities in surface water from the South Platte River near Denver, Colorado, USA. To evaluate the temporal and spatial distribution of selected contaminants of emerging concern, water samples were collected throughout 2018 and 2019 at 11 sites within the S. Platte River and surrounding tributaries with varying proximities to a major wastewater treatment plant (WWTP). Water samples were analyzed for pharmaceuticals, pesticides, steroid hormones...
Source: Environmental Pollution - August 24, 2021 Category: Environmental Health Authors: Jenna E Cavallin Jon Beihoffer Brett R Blackwell Alexander R Cole Drew R Ekman Rachel Hofer Aaron Jastrow Julie Kinsey Kristen Keteles Erin M Maloney Jordan Parman Dana L Winkelman Daniel L Villeneuve Source Type: research