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Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Elevated Aminotransferase Levels and Intracerebral Hemorrhage Deaths in a General Japanese Population
Int Heart J. 2023;64(4):678-683. doi: 10.1536/ihj.23-027.ABSTRACTAlthough chronic liver disease has been associated with cardiovascular disease, to which metabolic syndrome might be related, intracerebral hemorrhage (ICH) generally has not been focused. Associations of chronic liver disease assessed by aspartate (AST) and alanine (ALT) aminotransferase levels with ICH deaths were examined using 15,952 subjects without a history of cardiovascular disease who underwent annual health checkups in 1997 in Japan. Proportional hazards regression analyses adjusted for age, sex, hypertension, current smoking, diabetes mellitus, dri...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Hisako Tsuji Ichiro Shiojima Source Type: research

One-Year Outcome of Patients with Chest Pain in the Rule-Out Group According to the 0-Hour/1-Hour Algorithm
Int Heart J. 2023;64(4):590-595. doi: 10.1536/ihj.23-076.ABSTRACTThe European Society of Cardiology recommends the 0/1-hour algorithm for risk stratification of patients with suspected non-ST-elevation myocardial infarction as class I, level B; however, there are few reports on the long-term prognosis, resulting in a rule-out group. We aimed to determine whether implementation of the 0-hour/1-hour algorithm is safe and effective in emergency department (ED) patients with possible acute coronary syndrome (ACS) through a 1-year follow-up period. Our study analyzed the 1-year follow-up data from a prospective pre-post study o...
Source: International Heart Journal - July 30, 2023 Category: Cardiology Authors: Shun Sasaki Kenji Inoue Masayuki Shiozaki Chien-Chang Lee Shuo-Ju Chiang Satoru Suwa Kentaro Fukuda Masaru Hiki Naozumi Kubota Hiroshi Tamura Manabu Sugita Masataka Sumiyoshi Tohru Minamino Source Type: research

Rationale and Design of Randomized Evaluation of Aggressive or Moderate Lipid Lowering Therapy with Pitavastatin in Coronary Artery Disease (REAL-CAD) Trial.
Authors: Miyauchi K, Kimura T, Shimokawa H, Daida H, Iimuro S, Iwata H, Ozaki Y, Sakuma I, Nakagawa Y, Hibi K, Hiro T, Fukumoto Y, Hokimoto S, Ohashi Y, Ohtsu H, Saito Y, Matsuzaki M, Nagai R, REAL-CAD Trial Investigaters Abstract Large-scale clinical trials in patients in Western countries with coronary artery disease (CAD) have found that aggressive lipid-lowering therapy using high-dose statins reduces cardiovascular (CV) events further than low-dose statins. However, such evidence has not yet been fully established in Asian populations, including in Japan. The Randomized Evaluation of Aggressive or Moderate Lip...
Source: International Heart Journal - March 6, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

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