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Tilt testing
Pract Neurol. 2023 Sep 19:pn-2023-003749. doi: 10.1136/pn-2023-003749. Online ahead of print.ABSTRACTTilt testing can help to diagnose unexplained syncope, by precipitating an episode during cardiac monitoring. The Italian protocol, now most widely used, involves giving sublingual nitroglycerine after 15 min, while monitoring beat-to-beat blood pressure (BP) and recording on video. Tilt testing is time-consuming but it is clinically useful and can guide therapy. Complications are rare. Syncope types include vasovagal syncope where BP falls after >3 min of tilt-up and later the heart rate falls; classic orthostatic hypot...
Source: Practical Neurology - September 19, 2023 Category: Neurology Authors: Paul N Cooper Richard Sutton Source Type: research

Highly purified cannabidiol in the treatment of drug-resistant epilepsies: A real-life impact on seizure frequency, quality of life, behavior, and sleep patterns from a single Italian center
Epilepsy Behav. 2023 Sep 5;147:109409. doi: 10.1016/j.yebeh.2023.109409. Online ahead of print.ABSTRACTSeizure frequency in treatment-resistant epilepsies seems to be decreased by cannabidiol (CBD), but contrasting data are available on its effect on sleep, behavior, and quality of life (QoL), and no data is reported on its effect on parental stress in patients with epilepsy (PWE). Thus, we conducted a retrospective study on a cohort of children and adults with drug-resistant epilepsy (DRE) who had been treated with highly purified, pharmaceutical-grade CBD to evaluate its effects on seizure frequency, QoL, behavior, paren...
Source: Epilepsy and Behaviour - September 7, 2023 Category: Neurology Authors: G Ferrera E Ricci A Vignoli M N Savini I Vigan ò V Chiesa D Caputo E Zambrelli F La Briola K Turner M P Canevini Source Type: research

Comparison of the status epilepticus severity score and the epidemiology-based mortality score in predicting 30-day mortality and status epilepticus cessation
CONCLUSIONS: EMSE seems superior to STESS in predicting 30-day mortality, particularly in specific patient categories. Conversely, there is no difference in the ability of these scores in predicting SE cessation, which is overall rather low.PMID:37625347 | DOI:10.1016/j.yebeh.2023.109388
Source: Epilepsy and Behaviour - August 25, 2023 Category: Neurology Authors: Francesco Brigo Arian Zaboli Giada Giovannini Simona Lattanzi Niccol ò Orlandi Gianni Turcato Stefano Meletti Source Type: research

The ReadFree tool for the identification of poor readers: a validation study based on a machine learning approach in monolingual and minority-language children
In this study, we validated the "ReadFree tool", a computerised battery of 12 visual and auditory tasks developed to identify poor readers also in minority-language children (MLC). We tested the task-specific discriminant power on 142 Italian-monolingual participants (8-13 years old) divided into monolingual poor readers (N = 37) and good readers (N = 105) according to standardised Italian reading tests. The performances at the discriminant tasks of the "ReadFree tool" were entered into a classification and regression tree (CART) model to identify monolingual poor and good readers. The set of classification rules extracted...
Source: Annals of Dyslexia - August 7, 2023 Category: Neurology Authors: Desir é Carioti Natale Adolfo Stucchi Carlo Toneatto Marta Franca Masia Milena Del Monte Silvia Stefanelli Simona Travellini Antonella Marcelli Marco Tettamanti Mirta Vernice Maria Teresa Guasti Manuela Berlingeri Source Type: research

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