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Effect of teleconsultation on the application of thrombolytic therapy in stroke patients in the emergency department
ConclusionsTeleconsultation was a successful and reliable strategy in assessing patients with ischemic stroke and making decisions for IV-tPA. Moreover, patient assessment via teleconsultation was less time consuming. The results of the study are promising for the use of teleconsultation in the future.
Source: Irish Journal of Medical Science - August 19, 2023 Category: General Medicine Source Type: research

Early neurological deterioration in acute ischemic stroke
ConclusionOur study showed END may be associated with poor functional outcome in AIS patients. Higher blood glucose at admission and low serum albumin may be statistically significant causing END. Future prospective cohort with larger sample size may confirm the findings.
Source: Irish Journal of Medical Science - August 10, 2023 Category: General Medicine Source Type: research

Short-term DAPT after coronary stenting has similar ischemic and bleeding outcomes as long-term DAPT: a 5-year population-based cohort study
ConclusionThere is no significant difference in both bleeding and ischemic outcomes in long-term DAPT as compared to short-term DAPT for first- and second-generation drug-eluting stents in a real-world population.
Source: Irish Journal of Medical Science - August 1, 2023 Category: General Medicine Source Type: research

Reminiscence therapy relieves anxiety, depression and boosts spiritual well-being in both stroke patients and their spouse caregivers: a randomized, controlled study
ConclusionsRT relieves anxiety, depression and boosts spiritual well-being in both stroke patients and their spouse caregivers.
Source: Irish Journal of Medical Science - July 19, 2023 Category: General Medicine Source Type: research

Frequency of inter-specialty consensus decisions and adherence to advice following discussion at a weekly neurovascular multidisciplinary meeting
ConclusionsThe high frequency of inter-specialty consensus regarding management and adherence to proposed treatment supports a collaborative/multidisciplinary model of care in patients with extracranial arterial stenoses. Service development should aim to shorten times between MDM discussion-intervention and optimise prevention of stroke/death.
Source: Irish Journal of Medical Science - April 21, 2023 Category: General Medicine Source Type: research

Left atrial appendage occlusion in an older population cohort
ConclusionWe report lower technical success and procedural success rates in an older population cohort than historically studied, 90% of whom had an absolute contraindication to oral anticoagulation, with higher CHADS2VaSc and HASBLED scores than commonly studied.
Source: Irish Journal of Medical Science - April 3, 2023 Category: General Medicine Source Type: research

The impact of the COVID-19 pandemic on the provision of endovascular thrombectomy for stroke: an Irish perspective
ConclusionsDespite the myriad of challenges presented by the pandemic, service provision at the primary Irish ESC, and the referring hospitals, has proven to be robust. Procedural time metrics were maintained whilst the expected reduction in number of EVTs performed did not materialise, there actually being a significant increase in number of EVTs performed in the pandemic ’s second year.
Source: Irish Journal of Medical Science - February 16, 2023 Category: General Medicine Source Type: research

Clinical phenotype of obstructive sleep apnea in older adults: a hospital-based retrospective study in China
ConclusionsThe presence of OSA in older adults was associated with significant abnormalities of sleep architecture, aggravated nocturnal hypoxia and increased risks of hypertension, CAD, and stroke, which can be distinguished as a unique clinical phenotype.
Source: Irish Journal of Medical Science - January 27, 2023 Category: General Medicine Source Type: research

PREP Plus combined postrehabilitation programme to support upper limb recovery in community-dwelling stroke survivors: protocol for a mixed-methods, cluster-assigned feasibility study
This study has been approved by the Health and Social Care Research Ethics Committee A, IRAS project ID (278620). Participants will provide informed consent prior to participating in the study. Information outlining the purpose of the study, what data will be collected and how the data will be managed will be provided. Results will be published in peer-reviewed journals and any published data will be available on the university data repository. The project management group will advise on different avenues for dissemination to ensure it reaches appropriate audiences. Trial registration number NCT05090163.
Source: BMJ Open - January 20, 2023 Category: General Medicine Authors: Pedlow, K., McDonough, S., Klempel, N., Hylands, J., Hughes, N., Campbell, Z., Eng, J. J., Stephenson, A., Kennedy, N. Tags: Open access, Rehabilitation medicine Source Type: research

MRA-detected intracranial atherosclerotic disease in patients with TIA and minor stroke
ConclusionThe MRA sequence provides additional value by increasing the detection of clinically important intracranial atherosclerotic disease which may inform management in patients with minor stroke and TIA.
Source: Irish Journal of Medical Science - July 15, 2022 Category: General Medicine Source Type: research

Intravascular lithotripsy-assisted PCI for severely calcified coronary lesions: evaluating the impact on quality of life and outcomes
ConclusionsCoronary IVL is a safe and effective adjunctive therapy for treating heavily calcified coronary lesions. This cohort shows high procedural success and a significant reduction in CCS angina at follow-up.
Source: Irish Journal of Medical Science - July 9, 2022 Category: General Medicine Source Type: research

The effect of pelvic floor muscle training on urinary incontinence in patients with stroke: a systematic review and meta-analysis
ConclusionsThe results demonstrated that PFMT had positive effects in terms of daytime urination frequency and incontinence. Although some studies have reported positive effects on symptoms, function, strength, and endurance, the generalizability of these results is controversial. Further studies should assess the quality-of-life and function with urinary incontinence and stroke-specific tools.
Source: Irish Journal of Medical Science - July 1, 2022 Category: General Medicine Source Type: research

The relationship between infarct volume and high sensitivity troponin I level in patients diagnosed with ischemic stroke
ConclusionsHs-troponin I may be an effective biomarker in predicting the prognosis of patients with acute ischemic stroke. Multicenter comprehensive prospective studies are warranted to obtain stronger results.
Source: Irish Journal of Medical Science - June 6, 2022 Category: General Medicine Source Type: research

Transcatheter aortic valve implantation-related infective endocarditis: experience from an Irish tertiary referral centre
ConclusionsThis Irish cohort of TAVI-IE exhibited a similar incidence and time to presentation compared to prior international registries; however, the 1-year mortality rate was comparatively lower. The need for rigorous dental clearance pre-TAVI and maintenance of dental health post-TAVI is underscored by the high prevalence of oral streptococcus species in this cohort.
Source: Irish Journal of Medical Science - May 3, 2022 Category: General Medicine Source Type: research

Investigating the association between inpatient stroke therapy and disability, destination on discharge, length of stay and mortality: a prospective cohort study using the Sentinel Stroke National Audit Programme
Conclusions Our findings suggest for stroke inpatients requiring therapy, ‘More is better’ may be overly simplistic. Strong limitations associated with analysis of routine data restrict further robust investigation of the therapy–response relationship. Robust prospective work is urgently needed to further investigate the relationships observed here.
Source: BMJ Open - April 1, 2022 Category: General Medicine Authors: Gittins, M., Lugo-Palacios, D. G., Vail, A., Bowen, A., Paley, L., Bray, B., Gannon, B., Tyson, S. Tags: Open access, Rehabilitation medicine Source Type: research

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