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Assessment of atherosclerosis in ischemic stroke by means of ultrasound of extracranial/intracranial circulation and serum, urine, and tissue biomarkers
Curr Med Chem. 2022 Aug 17. doi: 10.2174/0929867329666220817123442. Online ahead of print.ABSTRACTIt is a common practice to take into consideration: age, diabetes, smoking, treated and untreated systolic blood pressure, total cholesterol, high-density lipoprotein cholesterol for the prediction of atherosclerosis and stroke. There are, however, ultrasound markers in use for the assessment of atherosclerosis and the evaluation of stroke risk. Two areas of investigation are of interest: the carotid artery and the intracranial arterial circulation. Again, within the domain of the carotid artery, two ultrasonic markers have at...
Source: Atherosclerosis - August 18, 2022 Category: Cardiology Authors: Grigorios G Dimas Maria Zilakaki Argyrios Giannopoulos Stylianos Daios Nikolaos Kakaletsis Georgia Kaiafa Triantafyllos Didangelos Christos Savopoulos Kyriakos Ktenidis Thomas Tegos Source Type: research

Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke
In this study, we aimed at evaluating the prognostic value of serum SIRT6 levels in patients with acute ischemic stroke (AIS). Serum levels of SIRT6, collected within 72 h from symptom-onset, were measured in 317 consecutively enrolled AIS patients from the COSMOS cohort. The primary endpoint of this analysis was 90-day mortality. The independent prognostic value of SIRT6 was assessed with multivariate logistic and Cox proportional regression models. 35 patients (11%) deceased within 90-day follow-up. After adjustment for established risk factors (age, NIHSS, heart failure, atrial fibrillation, and C reactive protein), SIR...
Source: Atherosclerosis - November 28, 2022 Category: Cardiology Authors: Luca Liberale Stefano Ministrini Markus Arnold Yustina M Puspitasari Thomas Pokorny Georgia Beer Natalie Scherrer Juliane Schweizer Mirjam Christ-Crain Fabrizio Montecucco Giovanni G Camici Mira Katan Kahles Source Type: research

Abstract 009: The Impact of Participation in a Telestroke Network on In-hospital Mortality in Georgia Session Title: Abstract Oral Session: General
Conclusions: Acute ischemic stroke patients admitted in hospitals participating in a telestroke program had a more pronounced reduction in in-hospital mortality. However, telestroke coverage did not alter the effect of nighttime admission on in-hospital mortality.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Zhang, D., Ido, M. S., Shi, L., Green, D. Tags: Session Title: Abstract Oral Session: General Source Type: research

Investigation of Drug Eluting Stents performance in human atherosclerotic artery through in silico modeling
Annu Int Conf IEEE Eng Med Biol Soc. 2021 Nov;2021:5433-5436. doi: 10.1109/EMBC46164.2021.9629895.ABSTRACTAtherosclerosis is a chronic inflammatory disease associated with heart attack and stroke. It causes the growth of atherosclerotic plaques inside the arterial vessels, which in turn results to the reduction of the blood flow to the different organs. Drug-Eluting Stents (DES) are mesh-like wires, carrying pharmaceutical coating, designed to dilate and support the arterial vessel, restore blood flow and through the controlled local drug delivery inhibit neo-intimal thickening. In silico modeling is an efficient method of...
Source: Atherosclerosis - December 11, 2021 Category: Cardiology Authors: Vasileios S Loukas Georgia S Karanasiou Dimitrios Pleouras Savvas Kyriakidis Antonis I Sakellarios Arsen Semertzioglou Lambros K Michalis Dimitrios I Fotiadis Source Type: research

Pregnancy-related cardiovascular conditions and outcomes in a United States Medicaid population
Conclusion This US cohort of Medicaid-funded women have a high incidence of severe cardiovascular conditions during pregnancy. Cardiometabolic conditions of pregnancy conferred threefold higher odds of severe cardiovascular outcomes.
Source: Heart - September 12, 2022 Category: Cardiology Authors: Marschner, S., von Huben, A., Zaman, S., Reynolds, H. R., Lee, V., Choudhary, P., Mehta, L. S., Chow, C. K. Tags: Open access, Editor's choice Cardiac risk factors and prevention Source Type: research