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Specialty: Cardiology
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Total 288 results found since Jan 2013.

Importance of Considering Competing Risks in Time-to-Event Analyses: Application to Stroke Risk in a Retrospective Cohort Study of Elderly Patients With Atrial Fibrillation Original Articles
Conclusions: The incidence of death without stroke was 9-fold higher than that of stroke, leading to biased estimates of stroke risk with traditional time-to-event methods. Statistical methods that appropriately account for competing risks should be used to mitigate this bias.
Source: Circulation: Cardiovascular Quality and Outcomes - July 11, 2018 Category: Cardiology Authors: Abdel-Qadir, H., Fang, J., Lee, D. S., Tu, J. V., Amir, E., Austin, P. C., Anderson, G. M. Tags: Atrial Fibrillation, Epidemiology, Primary Prevention, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Telehealth for remote stroke management
This article reviews the rationale for telestroke networks and their current implementation in Canada. Telestroke networks enable stroke-specific procedures to be performed by less experiences physicians under the guidance of stroke neurology experts. The article also presents evidence that the safety and effectiveness of intravenous alteplase in community hospitals in a telestroke network seems to be comparable to that achieved in dedicated stroke centres. It is thus a viable option to guarantee an aging population access to stroke care across large geographic regions with faster treatment and access to more advanced trea...
Source: Canadian Journal of Cardiology - December 27, 2017 Category: Cardiology Source Type: research

Stroke in HIV
Publication date: Available online 6 December 2018Source: Canadian Journal of CardiologyAuthor(s): Milana Bogorodskaya, Felicia C. Chow, Virginia A. TriantAbstractStroke is a heterogeneous disease in persons living with HIV (PLWH). HIV is thought to increase the risk of stroke through both HIV-related and traditional stroke risk factors, which vary with respect to the patient’s age and clinical characteristics. Numerous studies show that detectable viremia and immunosuppression increase the risk of stroke across all ages while traditional risk factors are more common in the aging HIV population. As PLWH age and acquire t...
Source: Canadian Journal of Cardiology - December 6, 2018 Category: Cardiology Source Type: research

Elevated Incidence of Atrial Fibrillation and Stroke in Patients with Atrial Flutter – A Population-Based Study
Conclusions Patients with isolated atrial flutter develop atrial fibrillation and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation may therefore be warranted. Teaser We examine the incidence of atrial fibrillation and stroke in a large real-world cohort of patients with atrial flutter, and the impact of atrial flutter ablation. Patients with atrial flutter developed atrial fibrillation and stroke at a higher rate than the general population. Atrial flutter ablation ...
Source: Canadian Journal of Cardiology - January 6, 2018 Category: Cardiology Source Type: research

Integrating Individuals with Stroke into Cardiac Rehabilitation Following Traditional Stroke Rehabilitation: Promoting a Continuum of Care
Publication date: Available online 11 July 2018Source: Canadian Journal of CardiologyAuthor(s): Susan Marzolini, R. KinUnstructured AbstractIndividuals following stroke are at a high risk for a repeat stroke and for complications related to coronary artery disease. Indeed, stroke and coronary artery disease share many of the same risk factors. Unfortunately, patients become sedentary after stroke leading to cardiorespiratory deconditioning as well as muscle atrophy and weakness that leads to deterioration in metabolic, cardiorespiratory, and functional health. Access to intensive secondary prevention programs with a struct...
Source: Canadian Journal of Cardiology - July 12, 2018 Category: Cardiology Source Type: research

Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter —A Population-Based Study
Conclusions Patients with isolated atrial flutter develop AF and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation might therefore be warranted.
Source: Canadian Journal of Cardiology - May 26, 2018 Category: Cardiology Source Type: research

Elevated Incidence of Atrial Fibrillation and Stroke in Patients With Atrial Flutter—A Population-Based Study
ConclusionsPatients with isolated atrial flutter develop AF and stroke at a higher rate than the general population. Catheter ablation reduces but does not eliminate future AF incidence and stroke risk and continued anticoagulation after successful atrial flutter ablation might therefore be warranted.RésuméIntroductionOn ignore le risque d’accident vasculaire cérébral (AVC) dû au flutter auriculaire et sa relation avec la progression de la fibrillation auriculaire (FA). La présente étude décrit l’incidence de la FA et de l'AVC chez les patients atteints de flutter auriculaire, et montre si l’ablation du flutt...
Source: Canadian Journal of Cardiology - July 5, 2018 Category: Cardiology Source Type: research

The multiple causes of stroke in atrial fibrillation: Thinking broadly
Publication date: Available online 30 August 2018Source: Canadian Journal of CardiologyAuthor(s): Atlantic D’Souza, Kenneth S. Butcher, Brian H. BuckAbstract:Atrial Fibrillation (AF) is numerically the most important risk factor for stroke. It is well established that patients with AF have a five-fold increased risk of stroke relative to those without, and that anticoagulation reduces the risk of stroke by approximately two-thirds. Definitively attributing the mechanism of an individual stroke to AF is much more problematic, however. In fact, there is no way to reliably establish the etiology of any ischemic infarction. ...
Source: Canadian Journal of Cardiology - August 31, 2018 Category: Cardiology Source Type: research

XANTUS-EL: A real-world, prospective, observational study of patients treated with rivaroxaban for stroke prevention in atrial fibrillation in Eastern Europe, Middle East, Africa and Latin America
ConclusionsXANTUS-EL confirmed low stroke and major bleeding rates in patients with NVAF from EEMEA and Latin America. The population was younger but with more heart failure and hypertension than XANTUS; stroke/SE rate was similar but major bleeding lower.
Source: The Egyptian Heart Journal - October 5, 2018 Category: Cardiology Source Type: research

Association Between Patient and Physician Sex and Physician-Estimated Stroke and Bleeding Risks in Atrial Fibrillation
ConclusionsOur study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. While there were differences in agreement between physician estimated stroke risk and calculated CHADS2 scores, these differences were small and unlikely to impact clinical practice; further, despite any perceived differences in the accuracy of risk assessment by sex, most patients received anticoagulation.
Source: Canadian Journal of Cardiology - December 4, 2018 Category: Cardiology Source Type: research

Telehealth for Remote Stroke Management
Publication date: July 2018Source: Canadian Journal of Cardiology, Volume 34, Issue 7Author(s): Charlotte Zerna, Thomas Jeerakathil, Michael D. HillAbstractStroke is a leading cause of adult disability and the fourth leading cause of death in Canada. Most strokes are ischemic and functional outcome is highly time-dependent, making fast diagnosis and treatment initiation crucial. This poses a challenge in vast geographical areas where stroke neurology expertise is only available in urban centres. In this article we review the rationale for telestroke networks and their current implementation in Canada. Telestroke networks e...
Source: Canadian Journal of Cardiology - July 5, 2018 Category: Cardiology Source Type: research

Improving Door-to-needle Times in the Treatment of Acute Ischemic Stroke Across a Canadian Province: Methodology
Background: Alteplase is a proven medical treatment for acute ischemic stroke; however, the effectiveness of this treatment is highly time dependent. Therefore, it is imperative that hospitals treat acute ischemic stroke patients as quickly as possible. The measure, door-to-needle time, is the time from hospital arrival to when alteplase administration begins. Objective: The goal in the Canadian province of Alberta was to reduce the door-to-needle time to a median of 30 minutes and to increase the percent of patients treated within 60 minutes to 90%. Overview of Methodology: A modified version of Institute for Heal...
Source: Critical Pathways in Cardiology - February 13, 2019 Category: Cardiology Tags: Pathway Source Type: research

Blinded Randomized trial of Anticoagulation to prevent Ischemic stroke and Neurocognitive impairment in AF (BRAIN-AF): Methods and design
ConclusionBRAIN-AF will determine whether oral anticoagulation therapy with rivaroxaban compared with standard of care reduces the risk of stroke, TIA or cognitive decline in patients with non-valvular AF and a low risk of stroke.
Source: Canadian Journal of Cardiology - May 8, 2019 Category: Cardiology Source Type: research