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Androgen Deprivation Therapy and Risk of Cardiovascular Disease in Patients With Prostate Cancer Based on Existence of Cardiovascular Risk
CONCLUSIONS: Compared with GnRH agonists, the GnRH antagonist was found to be associated with a decreased risk of HF, specifically among patients with prior CVD. Among those with no prior CVD, the GnRH antagonist was associated with a decreased risk of IHD but an increased risk of arrhythmia.PMID:36791755 | DOI:10.6004/jnccn.2022.7083
Source: Cancer Control - February 15, 2023 Category: Cancer & Oncology Authors: Alice Dragomir Nawar Touma Jason Hu Sylvie Perreault Armen G Aprikian Source Type: research

Mortality and Morbidity Effects of Long-Term Exposure to Low-Level PM < sub > 2.5 < /sub > , BC, NO < sub > 2 < /sub > , and O < sub > 3 < /sub > : An Analysis of European Cohorts in the ELAPSE Project
CONCLUSIONS: Long-term exposure to PM2.5, NO2, and BC was positively associated with natural-cause and cause-specific mortality in the pooled cohort and the administrative cohorts. Associations were found well below current limit values and guidelines for PM2.5 and NO2. Associations tended to be supralinear, with steeper slopes at low exposures with no indication of a threshold. Two-pollutant models documented the importance of characterizing the ambient mixture with both NO2 and PM2.5. We mostly found negative associations with O3. In two-pollutant models with NO2, the negative associations with O3 were attenuated to esse...
Source: Cancer Control - September 15, 2022 Category: Cancer & Oncology Authors: Brunekreef Bert Strak Maciej Chen Jie J Andersen Zorana Atkinson Richard Bauwelinck Mariska Bellander Tom Boutron Marie-Christine Brandt J ørgen Carey Iain Cesaroni Giulia Forastiere Francesco Fecht Daniela Gulliver John Hertel Ole Hoffmann Barbara de Ho Source Type: research