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Specialty: Internal Medicine
Source: PLoS Medicine
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Fixed-dose combination antihypertensive medications, adherence, and clinical outcomes: A population-based retrospective cohort study
by Amol A. Verma, Wayne Khuu, Mina Tadrous, Tara Gomes, Muhammad M. Mamdani
BackgroundThe majority of people with hypertension require more than one medication to achieve blood pressure control. Many patients are prescribed multipill antihypertensive regimens rather than single-pill fixed-dose combination (FDC) treatment. Although FDC use may improve medication adherence, the impact on patient outcomes is unclear. We compared clinical outcomes and medication adherence with FDC therapy versus multipill combination therapy in a real-world setting using linked clinical and administrative databases. Methods and findingsWe cond...
Source: PLoS Medicine - June 11, 2018 Category: Internal Medicine Authors: Amol A. Verma Source Type: research
