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Neuromuscular and Muscle Metabolic Functions in MELAS Before and After Resistance Training: A Case Study
Conclusion To conclude, this study suggests a preserved plasticity in the skeletal muscle of a patient with MELAS. More importantly, Resistance Training appears to be a safe and effective method to increase skeletal muscle function in this patient population, and this effect is mediated by both neuromuscular and mitochondrial adaptations. However, particular attention and caution is needed in the interpretation of the data of this single case study and further studies are warranted including larger sample of patients. Ethics Statement For this case study the participant caregiver provided written informed consent. Auth...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Ambient Conditions Prior to Tokyo 2020 Olympic and Paralympic Games: Considerations for Acclimation or Acclimatization Strategies
This study was supported by ZonMw (Project: Thermo Tokyo: Beat the heat), Netherlands Organisation for Scientific Research (NWO) (Project: Citius, Altius, Sanius), and Heatshield, under EU Horizon 2020 grant agreement No 668786. Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Acknowledgments The authors thank Dr. Tatsuro Amano (Niigata University, Japan) for his assistance with translating the Japanese Meteorological Agency website. Footnotes ^ https://rdrr.io/g...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

An Evaluation of Personal Cooling Systems for Reducing Thermal Strain Whilst Working in Chemical/Biological Protective Clothing
Conclusion: The IV, PCM, and SLIV produced lower heart rate, mean skin, rectal and mean body temperatures in addition to improved work times compared to control. The WS did not improve work times possibly as a result of the cooling capacity of the suit abating, and magnifying thermal insulation. Considering the added time and resources required to implement combination cooling in the form of ice slurry and ice vest (SLIV), there was no significant additive effect for perception, cardiovascular strain, rectal temperature and total trial time relative to the phase change vest or ice vest alone. This may be a product of a &#x...
Source: Frontiers in Physiology - April 11, 2019 Category: Physiology Source Type: research

Elite Swimmers ’ Training Patterns in the 25 Weeks Prior to Their Season’s Best Performanc Insights Into Periodization From a 20-Years Cohort
Conclusion: Progressive increases in training load, macrocycles lasting about 14–15 weeks, and substantial volume of training at intensities ≤4 mmol⋅L-1 and>6 mmol⋅L-1, were associated with peak performance in elite swimmers. Introduction To achieve the fastest competition performances, elite coaches periodise athletes’ training loads over multi-year and annual training programs (Turner, 2011; Mujika et al., 2018). Periodization is the purposeful sequencing of training units (long-, medium-, and short-term training cycles and sessions) designed to produce cumulated adaptations tha...
Source: Frontiers in Physiology - April 9, 2019 Category: Physiology Source Type: research

Elite Swimmers ’ Training Patterns in the 25 Weeks Prior to Their Season’s Best Performances: Insights Into Periodization From a 20-Years Cohort
Conclusion: Progressive increases in training load, macrocycles lasting about 14–15 weeks, and substantial volume of training at intensities ≤4 mmol⋅L-1 and>6 mmol⋅L-1, were associated with peak performance in elite swimmers. Introduction To achieve the fastest competition performances, elite coaches periodise athletes’ training loads over multi-year and annual training programs (Turner, 2011; Mujika et al., 2018). Periodization is the purposeful sequencing of training units (long-, medium-, and short-term training cycles and sessions) designed to produce cumulated adaptations tha...
Source: Frontiers in Physiology - April 9, 2019 Category: Physiology Source Type: research