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Eosinophilia and predominant Th2 immune responses are rarely evident in disseminated tuberculosis
Conclusion: We could find no evidence of frequent asthma or heightened Th2 immunity (high blood eosinophils) in disseminated TB. It is possible that measuring blood counts at time of presentation is too late to detect any eosinophilia present earlier when they first acquired TB and failed to mount an early effective immune response. The eosinopaenia in these patients may reflect Th1 immune responses suppressing Th2 responses, and there is limited evidence that BCG vaccination may be able to suppress asthmatic inflammation.
Source: European Respiratory Journal - November 7, 2016 Category: Respiratory Medicine Authors: Pfeffer, P., Burman, M., Milton, V., Naidu, V., Vaghela, D., Kunst, H. Tags: 10.2 Tuberculosis Source Type: research
