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Specialty: ENT & OMF

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Total 2815 results found since Jan 2013.

The development of allergic rhinitis in children previously diagnosed as nonallergic rhinitis.
CONCLUSION: Children with NAR who had family history of atopy, persistent nasal symptoms, and symptoms triggered by aeroallergens should be reevaluated periodically for the development of AR. This study was part of the clinical trial NCT01068808 registered in www.clinicaltrials.gov. PMID: 23406600 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Veskitkul J, Vichyanond P, Visitsunthorn N, Jirapongsananuruk O Tags: Am J Rhinol Allergy Source Type: research

Bacterial pathogens in the nasopharynx, nasal cavity, and osteomeatal complex during wellness and viral infection.
CONCLUSION: This study defines the carriage rates of the three most common bacterial pathogens for acute sinusitis in the nasopharynx, nasal cavity, and OMC during illness and in the healthy state. PMID: 23406599 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Rawlings BA, Higgins TS, Han JK Tags: Am J Rhinol Allergy Source Type: research

Antibody deficiency in chronic rhinosinusitis: Epidemiology and burden of illness.
CONCLUSION: Screening for a primary immunodeficiency should be part of the diagnostic workup of refractory CRS, as its identification may allow for more effective long-term therapeutic options. PMID: 23406598 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Ocampo CJ, Peters AT Tags: Am J Rhinol Allergy Source Type: research

Impact of mitomycin C on the mRNA expression signatures of immunological biomarkers in eosinophilic nasal polyposis.
CONCLUSION: After the characterization of the expression signatures of immunologic biomarkers in ENP, we observed that the topical use of mitomycin C is important for the reestablishment of the immunologic microenvironment of a normal expression profile of biomarkers involved in ENP mucosal tissue. PMID: 23406597 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: de Castro MC, Rocha-Silva F, Gomes LI, Zauli DA, de Moraes Mourão M, de Castro MM, Guimarães RE, Teixeira-Carvalho A, Martins-Filho OA Tags: Am J Rhinol Allergy Source Type: research

Sinonasal epithelial cell expression of Toll-like receptor 9 is elevated in cystic fibrosis-associated chronic rhinosinusitis.
CONCLUSION: The significantly greater expression of sinonasal epithelial TLR9 in CF likely reflects increased antimicrobial innate immune activity in chronically colonized and frequently infected CF individuals. However, this finding contrasts with previously reported decreased epithelial TLR9 expression in eosinophilic CRS with nasal polyposis and may indicate differential modulation of innate immunity in Th1-predominent CF versus Th2-dominated CRS with nasal polyps, despite both being diseases of sinonasal mucosal inflammation. PMID: 23406596 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Melvin TA, Lane AP, Nguyen MT, Lin SY Tags: Am J Rhinol Allergy Source Type: research

Methotrexate induces apoptosis in nasal polyps via caspase cascades and both mitochondria-mediated and p38 mitogen-activated protein kinases/Jun N-terminal kinase pathways.
CONCLUSION: MTX induces apoptosis in NPs via caspase cascades and both mitochondria-mediated and p38 MAPK/JNK pathways. We suggest that MTX can be used to treat NPs. PMID: 23406595 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Cho HW, Park SK, Heo KW, Hur DY Tags: Am J Rhinol Allergy Source Type: research

Detection of surfactant proteins A, B, C, and D in human nasal mucosa and their regulation in chronic rhinosinusitis with polyps.
CONCLUSION: Based on these results, SPs appear to have an important function in immunologic and rheological process of the nasal mucosa and support the prospective therapeutic use of liposomal nasal sprays. PMID: 23406594 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Schicht M, Knipping S, Hirt R, Beileke S, Sel S, Paulsen F, Bräuer L Tags: Am J Rhinol Allergy Source Type: research

Rhinitis has an association with asthma in school children.
CONCLUSION: There was a close association between rhinitis and asthma in young children to adolescents. Asthma should be examined in children with rhinitis symptoms. PMID: 23406593 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Higuchi O, Adachi Y, Itazawa T, Ito Y, Yoshida K, Ohya Y, Odajima H, Akasawa A, Miyawaki T Tags: Am J Rhinol Allergy Source Type: research

Effects of histone deacetylase inhibitor on extracellular matrix production in human nasal polyp organ cultures.
CONCLUSION: These findings provide novel insights into the epigenetic regulation in myofibroblast differentiation and ECM production of nasal polyp. TSA could be a candidate of a therapeutic agent for reversing the TGF-beta1-induced ECM synthesis that leads to nasal polyp development. PMID: 23406592 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Cho JS, Moon YM, Park IH, Um JY, Kang JH, Kim TH, Lee SH, Kang HJ, Lee HM Tags: Am J Rhinol Allergy Source Type: research

Changes of histamine receptors and CC chemokines in nasal epithelial cells and fibroblasts after respiratory syncytial virus infection.
CONCLUSION: RSV infection increases the levels of all four HRs, especially H1R and H2R, as well as the levels of eotaxin and RANTES in nasal epithelial cells and fibroblasts. These findings suggest that RSV infection might cause respiratory tract hyperreactivity by increasing the content of HRs and CC chemokines. PMID: 23406591 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Jung SY, Shin SY, Eun YG, Kim SW, Cho JS Tags: Am J Rhinol Allergy Source Type: research

Plasma paraoxonase activity and oxidative stress and their relationship to disease severity in children with allergic rhinitis.
CONCLUSION: Plasma PON1 and TOS levels may serve as predictors of disease severity in children with AR and both of them appear to be attractive candidates for modulating inflammation in AR. PMID: 23406590 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Ozkaya E, Akduman H, Erenberk U, Demir A, Dundaroz MR Tags: Am J Rhinol Allergy Source Type: research

Serum eosinophil cationic protein level in Chinese subjects with nonallergic and local allergic rhinitis and its relation to the severity of disease.
CONCLUSION: The present study provides the first evidence that LAR exists in Chinese subjects. This study also suggests that eosinophils and ECP take part in the pathogenesis of NAR. A local examination for ECP and specific IgE in nasal lavage fluid or secretions in patients with LAR should be performed in a future study. PMID: 23406588 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Cheng KJ, Xu YY, Liu HY, Wang SQ Tags: Am J Rhinol Allergy Source Type: research

Effect of Onchocerca volvulus chitinase on MUC5B expression in human airway epithelial cells.
CONCLUSION: These results suggest that chitinase induces MUC5B expression by activation of the p38 MAPK signaling pathway in human airway epithelial cells. PMID: 23406586 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Song SY, Seo YJ, Kim YW, Park SY, Bae CH, Kim YD Tags: Am J Rhinol Allergy Source Type: research

The effect of sinus surgery with intensive follow-up on pathogenic sinus bacteria in patients with cystic fibrosis.
CONCLUSION: Extensive sinus surgery combined with intensive follow-up can eradicate pathogenic bacteria from CF sinuses. PMID: 23406585 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - January 1, 2013 Category: ENT & OMF Authors: Aanaes K, von Buchwald C, Hjuler T, Skov M, Alanin M, Johansen HK Tags: Am J Rhinol Allergy Source Type: research

Comparison of Clinical Data, CT, and Bone Histopathology in Unilateral Chronic Maxillary Sinusitis.
PMID: 23562208 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - March 1, 2013 Category: ENT & OMF Authors: Amedee RG Tags: Am J Rhinol Allergy Source Type: research