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Specialty: ENT & OMF
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Total 2815 results found since Jan 2013.
Measuring outcomes in rhinosinusitis.
CONCLUSION: The purpose of this study was to describe the various diagnostic criteria that are used to evaluate RS and their role in measuring outcomes.
PMID: 24980237 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Benninger MS, Hopkins C, Tantilipikorn P Tags: Am J Rhinol Allergy Source Type: research
In vitro studies of a distillate of rectified essential oils on sinonasal components of mucociliary clearance.
CONCLUSION: Basolateral application of a distillate of rectified essential oils standardized stimulates both chloride efflux and cilia beat frequency resulting in a synergistic effect dramatically augmenting mucociliary transport velocity. These in vitro data support the clinical efficacy of this phytopharmaceutical in respiratory inflammatory disorders.
PMID: 24980236 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Lai Y, Dilidaer D, Chen B, Xu G, Shi J, Lee RJ, Cohen NA Tags: Am J Rhinol Allergy Source Type: research
In the (sub)tropics Allergic Rhinitis and Its Impact on Asthma classification of allergic rhinitis is more useful than perennial-seasonal classification.
CONCLUSION: In a (sub)tropical country the SAR-PAR classification seems of limited value and bears poor relation with the INT-PER classification. INT is more frequent in the tropical zone. Because PER has been shown to relate to AR severity, clinical trials should select patients based on INT-PER combined with the severity cataloging because these make for a better treatment guide than SAR-PAR.
PMID: 24980234 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Larenas-Linnemann D, Michels A, Dinger H, Arias-Cruz A, Ambriz Moreno M, Bedolla Barajas M, Javier RC, Cid Del Prado Mde L, Cruz Moreno MA, Vergara LD, García Almaráz R, García-Cobas CY, Garcia Imperial DA, Muñoz RG, Hernandez Colín D, Linares Zapien Tags: Am J Rhinol Allergy Source Type: research
Azelastine desensitization of transient receptor potential vanilloid 1: A potential mechanism explaining its therapeutic effect in nonallergic rhinitis.
CONCLUSION: Azelastine, similar to capsaicin, exhibits direct activity on TRPV1 ion channels that may represent a novel mechanistic pathway explaining its clinical efficacy in NAR.
PMID: 24980233 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Singh U, Bernstein JA, Haar L, Luther K, Jones WK Tags: Am J Rhinol Allergy Source Type: research
Cigarette smoke promotes eosinophilic inflammation, airway remodeling, and nasal polyps in a murine polyp model.
CONCLUSION: Chronic exposure to CS aggravated eosinophilic inflammation and promoted airway remodeling and nasal polyp formation in a murine model of ERSwNPs. The underlying mechanism might involve up-regulated expression of VEGF and HIF-1-alpha.
PMID: 24980232 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Lee KI, Kim DW, Kim EH, Kim JH, Samivel R, Kwon JE, Ahn JC, Chung YJ, Mo JH Tags: Am J Rhinol Allergy Source Type: research
Chronic rhinosinusitis with nasal polyps and without nasal polyps is associated with increased expression of lysophosphatidic acid-related molecules.
CONCLUSION: LPA in human sinus mucosa may play important roles in the pathogenesis of CRS, contributing to produce CRS-related cytokines. LPA-related molecules were increased in CRS, which may attribute to CRS-related cytokines.
PMID: 24980231 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Park SJ, Jun YJ, Lee KJ, Hwang SM, Kim TH, Lee SH, Lee SH Tags: Am J Rhinol Allergy Source Type: research
Differences in initial immunoprofiles between recurrent and nonrecurrent chronic rhinosinusitis with nasal polyps.
In this study we investigate the cytokine profile in CRSwNPs that underwent FESS for the first time and recurrent CRSwNPs.
METHODS: Tissue samples (n = 21) of CRSwNP patients with no recurrence after the first surgery were randomly selected out of 131 primary FESS surgeries and compared with tissue samples (n = 15) from patients who had a first and second surgery because of recurrence. Interleukin (IL)-1beta, IgE, specific IgE, IL-5, interferon (IFN) gamma, IL-6, IL-17, transforming growth factor (TGF) beta1, and myeloperoxidase were measured on tissue homogenates.
RESULTS: Levels of IgE, specific IgE to Staphylo...
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Van Zele T, Holtappels G, Gevaert P, Bachert C Tags: Am J Rhinol Allergy Source Type: research
Expression of apoptosis mediators p53 and caspase 3, 7, and 9 in chronic rhinosinusitis with nasal polyposis.
CONCLUSION: The reduced expression of these apoptosis factors in CRSwNPs might be related to higher proliferation and the perpetuation of inflammatory cells hindering the control of the disease. A better understanding of the possible influence of apoptosis factors on CRSwNPs could provide rationale for future therapies.
PMID: 24980229 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Küpper DS, Valera FC, Malinsky R, Milanezi CM, Silva JS, Tamashiro E, Anselmo-Lima WT Tags: Am J Rhinol Allergy Source Type: research
Editorial: The pathophysiology of sinonasal conditions and novel therapeutic options.
PMID: 24980228 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Peters AT Tags: Am J Rhinol Allergy Source Type: research
Neonatal vaccination with plasmid DNA encoding Cyn d 1 effectively prevents allergic responses in mice.
CONCLUSION: This study shows the prophylactic effects of DNA vaccine encoding Bermuda grass pollen allergen Cyn d 1 on specific IgE responses in neonatal mice.
PMID: 24980227 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Huang CF, Wu CC, Chu DM, Chang ZN, Chue FL, Peng HJ Tags: Am J Rhinol Allergy Source Type: research
Comparison of topical anesthetic effects of lidocaine, prilocaine, ropivacaine, and bupivacaine in transnasal fiberoptic nasopharyngolaryngoscopy.
CONCLUSION: To provide ideal examination comfort and optimum patient tolerability during TFL evaluation of upper respiratory airway topical lidocaine and prilocaine applications were found to be more efficacious and effective medication for anesthesia of the intranasal mucosa compared with bupivacaine and ropivacaine solutions.
PMID: 24980226 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Ozkırış M, Aydın R, Gencer ZK, Saydam L Tags: Am J Rhinol Allergy Source Type: research
Histamine type 2 receptor expression on peripheral blood regulatory lymphocytes in patients with allergic rhinitis treated with specific immunotherapy.
CONCLUSION: Natural pollen exposure results in up-regulation of H2R in Treg cells. Immunotherapy might transiently decrease the number of Treg-H2R(+) cells in the blood, which may be associated with their migration to the peripheral tissues. This study was part of the clinical trial registered in www.clinicaltrials.gov.
PMID: 24980224 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Ciebiada M, Kasztalska K, Gorska-Ciebiada M, Górski P Tags: Am J Rhinol Allergy Source Type: research
Chronic cholesterol depletion by lovastatin suppresses MUC5AC gene expression in human airway epithelial cells.
CONCLUSION: Chronic cholesterol depletion in the plasma membrane of NCI-H292 cells may be considered an antihypersecretory method, because it effectively inhibits mucin gene expression of human airway epithelial cells.
PMID: 24980223 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Lee EJ, Song KJ, Kwon JH, Park AY, Jo KH, Kim KS Tags: Am J Rhinol Allergy Source Type: research
Inhibitory effect of prostaglandin E2 on the migration of nasal fibroblasts.
CONCLUSION: PGE2 inhibited the migration of nasal fibroblasts via the EP2 and EP4 receptors, and this inhibition was mediated by cAMP elevation. Targeting specific EP receptors could offer therapeutic opportunities for conditions such as delayed wound healing after nasal surgery.
PMID: 24980222 [PubMed - in process]
Source: American Journal of Rhinology and Allergy - May 1, 2014 Category: ENT & OMF Authors: Shin JM, Park IH, Moon YM, Hong SM, Cho JS, Um JY, Lee HM Tags: Am J Rhinol Allergy Source Type: research
A randomized trial of mupirocin sinonasal rinses versus saline in surgically recalcitrant staphylococcal chronic rhinosinusitis.
PMID: 25010886 [PubMed - as supplied by publisher]
Source: American Journal of Rhinology and Allergy - January 1, 2014 Category: ENT & OMF Authors: Amedee RG Tags: Am J Rhinol Allergy Source Type: research
