Filtered By:
Therapy: Cancer Therapy
This page shows you your search results in order of relevance. This is page number 2.
Order by Relevance | Date
Total 225 results found since Jan 2013.
Epigallocatechin-3-gallate Enhances the Efficacy of MicroRNA-34a Mimic and MicroRNA-93 Inhibitor Co-transfection in Prostate Cancer Cell Line
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):612-623. doi: 10.18502/ijaai.v19i6.4930.ABSTRACTThe potential role of microRNAs (miRNA or MIR) as therapeutic molecules has moved them from basic research to the field of cancer therapy. High expression of miR-93 and low expression of miR-34a have previously been indicated in prostate cancer (PC), which is the second leading cause of cancer-related death in men. Androgen receptor (AR) and prostate-specific antigen (PSA) play key roles in the initiation and progression of this cancer. Therefore, this study aimed to investigate the effects of the transfection and co-transfecti...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Hossein Mokhtari Bahram Yaghmaei Majid Sirati-Sabet Narjes Jafari Alireza Mardomi Saeid Abediankenari Abdolkarim Mahrooz Source Type: research
Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells
Iran J Allergy Asthma Immunol. 2020 Aug 25;19(4):426-436. doi: 10.18502/ijaai.v19i4.4117.ABSTRACTSeveral studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment. Lipopolysaccharide (LPS), as a ligand for Toll-like receptor 4 (TLR-4), can modify immune responses in different cancers. Although multiple studies have been performed in this area, the effect of LPS on tumor cells remains controversial. In the present study, the cytotoxic effects of 5-fluorouracil (5-FU), with or without LPS, were evaluated in human breast ca...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Negin Nokhandani Mahdieh Naghavi Alhosseini Ali Memarian Homa Davoodi Source Type: research
Epigallocatechin-3-gallate Enhances the Efficacy of MicroRNA-34a Mimic and MicroRNA-93 Inhibitor Co-transfection in Prostate Cancer Cell Line
Iran J Allergy Asthma Immunol. 2020 Dec 19;19(6):612-623. doi: 10.18502/ijaai.v19i6.4930.ABSTRACTThe potential role of microRNAs (miRNA or MIR) as therapeutic molecules has moved them from basic research to the field of cancer therapy. High expression of miR-93 and low expression of miR-34a have previously been indicated in prostate cancer (PC), which is the second leading cause of cancer-related death in men. Androgen receptor (AR) and prostate-specific antigen (PSA) play key roles in the initiation and progression of this cancer. Therefore, this study aimed to investigate the effects of the transfection and co-transfecti...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Hossein Mokhtari Bahram Yaghmaei Majid Sirati-Sabet Narjes Jafari Alireza Mardomi Saeid Abediankenari Abdolkarim Mahrooz Source Type: research
Combination of 5-fluorouracil and Lipopolysaccharide Synergistically Induces Cytotoxicity and Apoptosis in MCF-7 Human Breast Cancer Cells
Iran J Allergy Asthma Immunol. 2020 Aug 25;19(4):426-436. doi: 10.18502/ijaai.v19i4.4117.ABSTRACTSeveral studies have been conducted to find suitable combinations of drugs to increase the efficacy of chemotherapy and reduce the resistance of tumor cells to treatment. Lipopolysaccharide (LPS), as a ligand for Toll-like receptor 4 (TLR-4), can modify immune responses in different cancers. Although multiple studies have been performed in this area, the effect of LPS on tumor cells remains controversial. In the present study, the cytotoxic effects of 5-fluorouracil (5-FU), with or without LPS, were evaluated in human breast ca...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Negin Nokhandani Mahdieh Naghavi Alhosseini Ali Memarian Homa Davoodi Source Type: research
Tumor Microenvironment Changing through Application of MicroRNA-34a Related Mesenchymal Stem Cells Conditioned Medium: Modulation of Breast Cancer Cells toward Non-aggressive Behavior
Iran J Allergy Asthma Immunol. 2021 Apr 17;20(2):221-232.ABSTRACTConditioned medium (CM) derived from mesenchymal stem cells (MSCs) contains bioactive molecules including microRNAs (miRs) that could be a potential tool for controlling cancer cells' behavior. Due to the properties of CM, this study assesses the effects of miR-34a related MSC-CM on tumor behavior through the evaluation of migration, invasion, apoptosis, and PDL1 expression in breast cancer cell lines. The miR-34a overexpression vector or scramble control was produced using lentiviral vectors, DNA cloning, and the transfection of the HEK-293T cell line. It wa...
Source: Iranian Journal of Allergy, Asthma and Immunology - April 27, 2021 Category: Allergy & Immunology Authors: Katayoun Bahman Soufiani Ali Akbar Pourfathollah Mahin Nikougoftar Zarif Ehsan Arefian Source Type: research
