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Quantifying the increasing use of anti-vascular endothelial growth factor therapy in ophthalmology
CONCLUSION: Bevacizumab is one of the most far reaching drugs in ophthalmology and even medicine, but it is not yet supported by high quality evidence. The much higher cost of ranibizumab may be responsible for bevacizumab's popularity among eye specialists. Patients should be fully informed about the off-label use of bevacizumab and the associated risks with its use.PMID:22815647 | PMC:PMC3399721
Source: McGill Journal of Medicine : MJM - July 21, 2012 Category: Universities & Medical Training Authors: Jonathan A Micieli Andrew Micieli Source Type: research
A rat model for retinitis pigmentosa with rapid retinal degeneration enables drug evaluation in vivo
CONCLUSIONS: In this RP model, the time to onset of retinal degeneration was less than that of previously reported RP models with other rhodopsin mutations, enabling quicker in vivo evaluation of drug efficacy. Administration of rapamycin delayed the photoreceptor cell degeneration by approximately 1 day.PMID:34088267 | PMC:PMC8176615 | DOI:10.1186/s12575-021-00150-y
Source: Biological Procedures Online - June 5, 2021 Category: Molecular Biology Authors: Chisato Inoue Tamaki Takeuchi Akira Shiota Mineo Kondo Yuji Nshizawa Source Type: research
Quantifying the increasing use of anti-vascular endothelial growth factor therapy in ophthalmology
CONCLUSION: Bevacizumab is one of the most far reaching drugs in ophthalmology and even medicine, but it is not yet supported by high quality evidence. The much higher cost of ranibizumab may be responsible for bevacizumab's popularity among eye specialists. Patients should be fully informed about the off-label use of bevacizumab and the associated risks with its use.PMID:22815647 | PMC:PMC3399721
Source: McGill Journal of Medicine : MJM - July 21, 2012 Category: Universities & Medical Training Authors: Jonathan A Micieli Andrew Micieli Source Type: research
