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DDIWAS: High-throughput electronic health record-based screening of drug-drug interactions
ConclusionsIn this proof-of-concept study, we demonstrate the value of incorporating information mined from existing allergy lists to detect DDIs in a real-world clinical setting. Since allergy lists are routinely collected in EHRs, DDIWAS has the potential to detect and validate DDI signals across institutions.
Source: Journal of the American Medical Informatics Association - March 13, 2021 Category: Information Technology Source Type: research

Abstract 004: Electronic Health Record-Based Overestimation of Failure to Prescribe Statins in Patients With Coronary Artery Disease in a Large, Academic, Multispecialty Clinic Practice Session Title: Abstract Oral Session: QCOR 2017 Young Investigator Award Finalists
Conclusions: Among outpatients with presumed CAD who were identified by EHR data query as "failures" to receive statin prescriptions, an estimated fewer than one-third constituted a true gap in care. These findings raise concern about the accuracy of EHR data query in measuring performance in the Meaningful Use era.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Shin, E. Y., Ochuko, P., Bhatt, K., Howard, B., McGorisk, G., Delaney, L., Langdon, K., Khosravanipour, M., Nambi, A., Grahovec, A., Morris, D., Castellano, P., Shaw, L., Sperling, L., Goyal, A. Tags: Session Title: Abstract Oral Session: QCOR 2017 Young Investigator Award Finalists Source Type: research

Drug Allergies Documented in Electronic Health Records of a Large Healthcare System
ConclusionFemales and white patients may be more likely to experience a reaction from common medications. An increase in reported allergies to ACE inhibitors and statins is noteworthy.This article is protected by copyright. All rights reserved.
Source: Allergy - March 10, 2016 Category: Allergy & Immunology Authors: Li Zhou, Neil Dhopeshwarkar, Kimberly G Blumenthal, Foster Goss, Maxim Topaz, Sarah P Slight, David W Bates Tags: Original Article: Epidemiology and Genetics Source Type: research

Clinicians’ Reports in Electronic Health Records Versus Patients’ Concerns in Social Media: A Pilot Study of Adverse Drug Reactions of Aspirin and Atorvastatin
Conclusion Future studies should develop further natural language methods for a more detailed data analysis (i.e., identifying causality and temporal aspects in the social media data).
Source: Drug Safety - December 29, 2015 Category: Drugs & Pharmacology Source Type: research

Rising drug allergy alert overrides in electronic health records: an observational retrospective study of a decade of experience
Conclusions These findings underline the urgent need for more efforts to provide more accurate and relevant drug allergy alerts to help reduce alert override rates and improve alert fatigue.
Source: Journal of the American Medical Informatics Association - November 17, 2015 Category: Information Technology Authors: Topaz, M., Seger, D. L., Slight, S. P., Goss, F., Lai, K., Wickner, P. G., Blumenthal, K., Dhopeshwarkar, N., Chang, F., Bates, D. W., Zhou, L. Tags: Research and Applications Source Type: research