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Infectious Disease: Rotavirus
Nutrition: Sodium

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Total 2 results found since Jan 2013.

Sodium butyrate protects against rotavirus-induced intestinal epithelial barrier damage by activating AMPK-Nrf2 signaling pathway in IPEC-J2 cells
Int J Biol Macromol. 2022 Dec 21:S0141-8130(22)03130-0. doi: 10.1016/j.ijbiomac.2022.12.219. Online ahead of print.ABSTRACTRotavirus (RV) mainly infects intestinal epithelial cells, which leads to diarrhea in newborn piglets with dysfunction in the intestinal mucosal mechanical barrier. Sodium butyrate (SB) is one of the metabolites excreted by gut microbes. However, the protective effect of SB on RV infection induced intestinal mucosal mechanical barrier injury and its potential mechanism has not been well elucidated. In the present study, IPEC-J2 cells with RV infection was a model of intestinal mucosal mechanical barrie...
Source: International Journal of Biological Macromolecules - December 24, 2022 Category: Biochemistry Authors: Xia Dong Yi Wang Xiaoxiao Zhu Linyuan Shen Lei Chen Lili Niu Mailin Gan Shunhua Zhang Ming Zhang Jun Jiang Daiwen Chen Li Zhu Ye Zhao Source Type: research