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Encephalitis: parenchymal leucocytes in infectious, immune and unknown cause
Conclusions Our study describes potentially important differences in the relative leucocyte populations in the parenchyma of patients with encephalitis, which may have diagnostic and therapeutic implications. Further studies are planned to distinguish invading macrophage/monocytes from resident microglia in a transgenic murine model.
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 14, 2016 Category: Neurosurgery Authors: Daramola, O., Rathi, N., Michael, B., Griffiths, M., Moxham, N., Benjamin, L., Crooks, D., Solomon, T. Tags: Immunology (including allergy), Infection (neurology), Radiology, Surgical diagnostic tests ABN Annual Meeting, 17-19 May 2016, The Brighton Centre, Brighton Source Type: research

Autologous haematopoietic stem cell transplantation for aggressive multiple sclerosis: the Swedish experience
Conclusions HSCT is a very effective treatment of inflammatory active MS and can be performed with a high degree of safety at experienced centres.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Burman, J., Iacobaeus, E., Svenningsson, A., Lycke, J., Gunnarsson, M., Nilsson, P., Vrethem, M., Fredrikson, S., Martin, C., Sandstedt, A., Uggla, B., Lenhoff, S., Johansson, J.-E., Isaksson, C., Hagglund, H., Carlson, K., Fagius, J. Tags: Immunology (including allergy), Multiple sclerosis Source Type: research

Herpes encephalitis complicated by cerebral haemorrhage
Case report A 46-year-old, previously well, right-handed man presented with a 1 week history of headache, vomiting and confusion. On examination his temperature was 38.3°C, Glasgow Coma Scale score was 14/15 (E4V4M6) and he was severely expressively dysphasic. There was no limb weakness. Initial blood tests, including C reactive protein, were normal. Cranial CT revealed a hypodense area in the left anteromedial temporal lobe (figure 1). Microscopy of CSF from a lumbar puncture showed a pleocytosis (390x106/ml, lymphocytes 95%), with no organism. On a working diagnosis of herpes simplex virus (HSV) encephalitis, em...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 13, 2013 Category: Neurosurgery Authors: Lo, W. B., Wilcock, D. J., Carey, M., Albanese, E. Tags: Immunology (including allergy), HIV/AIDS, Coma and raised intracranial pressure, Epilepsy and seizures, Headache (including migraine), Infection (neurology), Pain (neurology) Neurological pictures Source Type: research