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The CXXC Motifs Are Essential for the Function of BosR in Borrelia burgdorferi
Discussion Structure-function analyses of numerous Fur proteins have revealed that Fur binds its target DNA as a dimer. Protein dimerization requires Zn, which is coordinated via the structural S1 site in the dimerization domain of Fur proteins. To date, it has been clearly demonstrated that different geometry and amino acid residues are used by Fur protein for coordinating Zn in the S1 site (Pohl et al., 2003; Lee and Helmann, 2006; Pecqueur et al., 2006; Traoré et al., 2006, 2009; Lucarelli et al., 2007; Ahmad et al., 2009; An et al., 2009; Carpenter et al., 2009; Jacquamet et al., 2009; Sheikh and Taylor, 2009;...
Source: Frontiers in cellular and infection microbiology - April 15, 2019 Category: Microbiology Source Type: research

Serum zinc level in bronchial asthma
Conclusion Measurement of zinc level could be recommended in asthmatic adults. proper supplementations of zinc can be useful in the management of asthmatic patients due to increase the effect of antioxidant defense system. However, further multi-centre studies with greater number of patients are needed to warrant the results of this study.
Source: Egyptian Journal of Chest Diseases and Tuberculosis - December 15, 2016 Category: Respiratory Medicine Source Type: research