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Explainer: Why the U.S. has banned funding for Chinese lab at center of pandemic origin dispute
In a move that has more symbolic than practical impact, the U.S. Department of Health and Human Services (HHS) has imposed new sanctions on a Chinese lab at the center of the debate about the origin of the COVID-19 pandemic. A nine-page HHS memo made public by a House subcommittee that ’s investigating the pandemic ’s origin suspends and proposes debarment of the Wuhan Institute of Virology (WIV) “from participating in United States Federal Government procurement and nonprocurement programs.” In effect, this bars WIV from receiving U.S. government funding now and possibly ever. The ...
Source: ScienceNOW - July 20, 2023 Category: Science Source Type: news

Study provides deeper insight into long COVID
This study is an important step toward defining long COVID beyond any one individual symptom, " said study author Dr. Leora Horwitz, director of the Center for Healthcare Innovation and Delivery Science and co-principal investigator for the RECOVER Clinical Science Core at NYU Langone Health. " This research definition — which may evolve over time — will serve as a foundation for scientific discovery and treatment design. "The researchers say studying the underlying biological mechanisms of long COVID is central to advancing informed interventions and identifying effective treatment strategies. In addition to establish...
Source: The University of Arizona: Health - May 30, 2023 Category: Universities & Medical Training Authors: mittank Source Type: research

Companies won ’t share COVID-19 shots, stalling future vaccine research
The U.S. government has tens of millions of unused doses of messenger RNA (mRNA) COVID-19 vaccines, regularly trashing shots as they pass their expiration dates. It’s a dismal reflection on recent vaccine uptake, but it’s also a serious roadblock for scientists testing and developing vaccines that could protect against future variants of SARS-CoV-2—and the next pandemic. Developers need existing vaccines as a benchmark to compare with new candidates. But government contracts with the vaccinemakers, and the companies’ own policies, prohibit the use of the vaccines for research purposes. “At this stage of the ...
Source: ScienceNOW - May 30, 2023 Category: Science Source Type: news

The COVID-19 virus mutated to outsmart key antibody treatments. Better ones are coming
In 2020, as the COVID-19 pandemic raged and other effective drugs were elusive, monoclonal antibodies (mAbs) emerged as a lifesaving treatment. But now, 3 years later, all the approvals for COVID-19–fighting antibodies have been rescinded in the United States, as mutations of the SARS-CoV-2 virus have left the drugs—which target parts of the original virus—ineffective. Researchers around the globe are now trying to revive antibody treatments by redesigning them to take aim at targets that are less prone to mutation. “There are new approaches that present a much more challenging task for the virus to evade,” ...
Source: ScienceNOW - May 24, 2023 Category: Science Source Type: news

NIH restarts bat virus grant suspended 3 years ago by Trump
Three years after then-President Donald Trump pressured the National Institutes of Health (NIH) to suspend a research grant to a U.S. group studying bat coronaviruses with partners in China, the agency has restarted the award. The new 4-year grant is a stripped-down version of the original grant to the EcoHealth Alliance, a nonprofit research organization in New York City, providing $576,000 per year. That 2014 award included funding for controversial experiments that mixed parts of different bat viruses related to severe acute respiratory syndrome (SARS), the coronavirus that sparked a global outbreak in 2002–04, a...
Source: ScienceNOW - May 8, 2023 Category: Science Source Type: news

Science takes back seat to politics in first House hearing on origin of COVID-19 pandemic
Some scientists and legislators might have hoped this morning’s U.S. congressional hearing on the origin of the COVID-19 pandemic would move beyond partisan politics and seriously investigate what has become a deeply divisive debate . But members of the House of Representatives’s Select Subcommittee on the Coronavirus Pandemic mostly hammered home long-standing Republican or Democratic talking points, shedding no new light on the central question: Did SARS-CoV-2 naturally jump from animals to humans or did the virus somehow leak from a laboratory in Wuhan, China? “It was very disappointing, and almost unbe...
Source: Science of Aging Knowledge Environment - March 8, 2023 Category: Geriatrics Source Type: research

Now in charge, House Republicans launch flurry of investigations
The new Republican majority in the U.S. House of Representatives is preparing to shine a bright light on science—and scientists. This week, it created two investigative panels that will scrutinize the country’s relationship with China and its response to the COVID-19 pandemic. Both committees are expected to grill many prominent scientists and federal research officials on their actions over the past several years. In approach and style, however, they are likely to be very different. The China panel, officially the Select Committee on Strategic Competition between the United States and the Chinese Communist Party,...
Source: Science of Aging Knowledge Environment - January 13, 2023 Category: Geriatrics Source Type: research

Dr. Anthony Fauci Is Stepping Down. Here ’s His Advice For His Successor
After Dr. Anthony Fauci steps down as head of the National Institute of Allergy and Infectious Diseases (NIAID) and chief medical advisor to President Biden on Dec. 31, he’ll leave behind a long and storied career. Ahead of his last day, he spoke to TIME from his office at the National Institutes of Health about what’s next for him—and his advice for whoever fills his shoes. This interview has been edited and condensed for clarity. TIME: You’re leaving your leadership positions in the federal government, but you aren’t retiring. What are you calling the next stage in your career? [time-brightc...
Source: TIME: Health - December 20, 2022 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Why the U.S. Doesn ’t Have a Nasal Vaccine for COVID-19
The U.S. led the world in quickly developing COVID-19 vaccines—one of the few bright spots in the country’s otherwise criticized response. But while injectable vaccines are effective in protecting people from getting sick with COVID-19, they are less able to block infection. In order to put the pandemic behind us, the world will need a way to stop infections and spread of the virus. That’s where a different type of vaccine, one that works at the places where the virus gets into the body, will likely prove useful. Here, though, the U.S. is losing its edge. In September, India approved a nasal COVID-19 vacc...
Source: TIME: Health - October 31, 2022 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

A New Lab-Made COVID-19 Virus Puts Gain-of-Function Research Under the Microscope
On October 14, a team of scientists at Boston University released a pre-print study reporting that they had created a version of SARS-CoV-2 combining two features of different, existing strains that boosted its virulence and transmissibility. Scientists and the public raised questions about the work, which refocused attention on such experiments, and prompted the U.S. government to investigate whether the research followed protocols for these kinds of studies. The concerns surround what is known as gain-of-function studies, in which viruses, bacteria, or other pathogens are created in the lab—either intentionally or ...
Source: TIME: Science - October 27, 2022 Category: Science Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

U.S. weighs crackdown on experiments that could make viruses more dangerous
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Source: ScienceNOW - October 19, 2022 Category: Science Source Type: news

Was a study that created a hybrid COVID-19 virus too risky?
The objective was to tease apart whether Omicron’s spike protein explains why it is less pathogenic (meaning it causes less severe disease). The answer could lead to improved COVID-19 diagnostic tests and better ways to manage the disease, the preprint authors say. Somewhat surprisingly, the hybrid virus killed eight of 10 infected mice, whereas mice infected with Omicron got sick but did not die. This suggests the mutations that make Omicron less pathogenic must involve changes in proteins other than the spike protein, the authors say. What are critics of the study saying? They question the scientific val...
Source: Science of Aging Knowledge Environment - October 18, 2022 Category: Geriatrics Source Type: research

Anthony Fauci, loved and hated, plots his next move: ‘I'm not going to sit in my house’
In 1984, when Anthony Fauci took over as head of the National Institute of Allergy and Infectious Diseases (NIAID), his wife gave him a plant for the new office. Both the palm and the 81-year-old physician are still there, the giant plant now crowding the office of one of the most celebrated—and polarizing—scientific figures in U.S. history. But not for much longer. Fauci announced on 22 August that he would step down at the end of the year from both NIAID and his post as the chief medical adviser to President Joe Biden. “What am I going to do with this plant? It’s a monster. I can’t fit it in any other plac...
Source: ScienceNOW - September 1, 2022 Category: Science Source Type: news

Anthony Fauci, loved and hated, plots his next move: ‘I’m not going to sit in my house’
In 1984, when Anthony Fauci took over as head of the National Institute of Allergy and Infectious Diseases (NIAID), his wife gave him a plant for the new office. Both the palm and the 81-year-old physician are still there, the giant plant now crowding the office of one of the most celebrated—and polarizing—scientific figures in U.S. history. But not for much longer. Fauci announced on 22 August that he would step down at the end of the year from both NIAID and his post as the chief medical adviser to President Joe Biden. “What am I going to do with this plant? It’s a monster. I can’t fit it in any other plac...
Source: ScienceNOW - September 1, 2022 Category: Science Source Type: news

Almost everything Tucker Carlson said about Anthony Fauci this week was misleading or false
Tucker Carlson, a political commentator on Fox News, has long assailed Anthony Fauci for his role in the U.S. government’s response to the COVID-19 pandemic during both former President Donald Trump’s and President Joe Biden’s administrations. But on 22 August, when Fauci announced he would be retiring from his jobs as director of the U.S. National Institute of Allergy and Infectious Diseases (NIAID) and chief medical adviser to the president at the end of year, the Tucker Carlson Tonight host laid into him like never before. Carlson asserted Fauci had committed “very serious crimes” and said he “app...
Source: ScienceNOW - August 25, 2022 Category: Science Source Type: news

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