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Steroid avoidance or withdrawal for pancreas and pancreas with kidney transplant recipients.
CONCLUSIONS: There is currently insufficient evidence for the benefits and harms of steroid withdrawal in pancreas transplantation in the three RCTs (144 patients) identified. The results showed uncertain results for short-term risk of rejection, mortality, or graft survival in steroid-sparing strategies in a very small number of patients over a short period of follow-up. Overall the data was sparse, so no firm conclusions are possible. Moreover, the 13 observational studies findings generally concur with the evidence found in the RCTs. PMID: 25220222 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - September 15, 2014 Category: Journals (General) Authors: Montero N, Webster AC, Royuela A, Zamora J, Crespo Barrio M, Pascual J Tags: Cochrane Database Syst Rev Source Type: research