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Infectious Disease: Pandemics

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Total 1816 results found since Jan 2013.

Relationship between Bacillus Calmette Guerin Vaccination Policy and Coronavirus Disease-2019 (COVID-19) Incidence
Iran J Allergy Asthma Immunol. 2021 Feb 11;20(1):106-113. doi: 10.18502/ijaai.v20i1.5417.ABSTRACTBacillus Calmette Guerin (BCG) was designed for protecting children against tuberculosis. Also, it can protect against other infectious diseases through the induction of trained immunity. Due to its heterologous protective effects, the BCG vaccine has been proposed as atreatment option for coronavirus disease-2019 (COVID-19). Epidemiological studies have found that countries without BCG vaccination policy have experienced higher mortality rates related toCOVID-19 infection than those with BCG vaccination policy. However, there ...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 27, 2021 Category: Allergy & Immunology Authors: Soheila Alyasin Zahra Kanannejad Hossein Esmaeilzadeh Hesamedin Nabavizadeh Mohammad Amin Ghatee Reza Amin Source Type: research

COVID-19 Associated Multisystem Inflammatory Syndrome: A Systematic Review and Meta-analysis
This study was aimed to describe clinical manifestation and outcomes of MIS-C associated with COVID-19. This systematic review and meta-analysis were conducted on all available literature until July 3rd, 2020. The screening was done by using the following keywords: ("novel coronavirus" Or COVID-19 or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus) and ("MIS-C" or "multisystem inflammatory" or Kawasaki). Data on gender, ethnicity, clinical presentations, need for mechanical ventilation or admission to intensive care unit (ICU), imaging, cardiac complications, and COVID-19 laboratory results were...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Ashkan Baradaran Abdolreza Malek Nasrin Moazzen Zahra Abbasi Shaye Source Type: research

Evaluating the Immune Response of Recombinant H1N1 Hemagglutinin with MF59 Adjuvant in Animal Model as a Novel Alternative to the Influenza Vaccine
This study examines the potential function of formulated H1N1 hemagglutinin with MF59 adjuvant against A/PR/8/34 (H1N1). To this end, a recombinant hemagglutinin (rHA) gene of influenza A virus was designed and expressed in SF9 cell by the Baculovirus expression system. Four groups of mice were immunized by rHA in combination with MF59, Alum adjuvant, and virus split only. The immunized mice subsequently used for the humoral immune assay and the results compared with untreated mice (negative group). Besides, both treated and control mice groups were challenged with mouse-adapted influenza virus A/PR/8/34(H1N1) through the ...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Niloufar Rashedi Morteza Taghizadeh Parisa Mohamadynejad Mehdi Mahdavi Reza Jalalirad Source Type: research

Variable Clinical Manifestations of COVID-19: Viral and Human Genomes Talk
Iran J Allergy Asthma Immunol. 2020 Oct 18;19(5):456-470. doi: 10.18502/ijaai.v19i5.4461.ABSTRACTThe new coronavirus, known as "SARS-CoV-2"; is the cause of one of the most prevalent infectious viral diseases that was recently announced pandemic by the world health organization. Ongoing research in the fields of prevention, management, and therapy establishes a functional scaffold for clinics during the time of crisis. To obtain this goal, it is necessary that all pathophysiologic aspects of COVID-19 from infection to predisposing backgrounds of infection be identified, so that all the ambiguities of researchers regarding ...
Source: Iranian Journal of Allergy, Asthma and Immunology - January 19, 2021 Category: Allergy & Immunology Authors: Zeinab Imani-Saber Hajar Vaseghi Mojdeh Mahdian Fatemeh Safari Mohsen Ghadami Source Type: research

Relationship between Bacillus Calmette Guerin Vaccination Policy and Coronavirus Disease-2019 (COVID-19) Incidence
Iran J Allergy Asthma Immunol. 2021 Feb 11;20(1):106-113. doi: 10.18502/ijaai.v20i1.5417.ABSTRACTBacillus Calmette Guerin (BCG) was designed for protecting children against tuberculosis. Also, it can protect against other infectious diseases through the induction of trained immunity. Due to its heterologous protective effects, the BCG vaccine has been proposed as atreatment option for coronavirus disease-2019 (COVID-19). Epidemiological studies have found that countries without BCG vaccination policy have experienced higher mortality rates related toCOVID-19 infection than those with BCG vaccination policy. However, there ...
Source: Iranian Journal of Allergy, Asthma and Immunology - February 27, 2021 Category: Allergy & Immunology Authors: Soheila Alyasin Zahra Kanannejad Hossein Esmaeilzadeh Hesamedin Nabavizadeh Mohammad Amin Ghatee Reza Amin Source Type: research