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Source: Turkish Journal of Medical Sciences
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Total 11368 results found since Jan 2013.
Does apocynin increase liver regeneration in the partial hepatectomy model?
DISCUSSION: Histopathology, immunohistochemistry, and biochemistry results of this study revealed that apocynin has a protective effect on enhancing liver regeneration in partial hepatectomy cases in rats.PMID:37476910 | DOI:10.55730/1300-0144.5627
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Y ılmaz Bilgiç Burhan Hakan Kanat Onural Özhan Azibe Y ıldız Zeynep Aksungur Mehmet Erman Erdemli Nigar Vard ı Yusuf T ürköz Ahmet Sami Akbulut Adem K öse Hakan Parlakp ınar Source Type: research
The effect of hydrochlorothiazide on the recurrence of nonmelanoma skin cancer: a 7-year retrospective study comprising 300 patients
This study aims to investigate the association between HCTZ use and recurrence in patients with NMSC.METHODS: We identified cases with NMSC from our hospital archives during the period between 2013 and 2019. Patients were divided into groups according to the pathological diagnosis, HCTZ use, and recurrence. Multivariable analysis was performed to determine factors associated with recurrence in BCC and SCC.RESULTS: Recurrences of BCC were significantly higher in HCTZ users with ORs of 4.839221 (95% confidence interval [CI], 1.22-19.12).In HCTZ users, NMSC cases were associated with increased age (p < 0.001 for both BCC a...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Burak Özkan S üleyman Savran Kadri Ak ıncı Abbas Albayati Pinar İncel Uysal Ahmet Çağrı Uysal Source Type: research
The role of endobronchial ultrasonography elastography in the diagnosis of hilar and mediastinal lymph nodes
DISCUSSION: The diagnostic accuracy of EBUS elastography is high enough to distinguish malignant LN from benign ones with the SR option. When compared with EBUS-B mode sonographic findings, it was found to have a higher diagnostic yield.PMID:37476908 | DOI:10.55730/1300-0144.5634
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Bar ış Demirkol Elif Tanr ıverdi Şule Gül Aysu Sinem Ko ç Elife Akg ün Ayt ül Hande Yardımcı K ürşad Nuri Baydili Erdo ğan Çetinkaya Source Type: research
T1 relaxation time is prolonged in healthy aging: a whole brain study
DISCUSSION: T1 mapping provides a practical quantitative MRI (qMRI) methodology for studying the tissue characteristics in healthy aging. T1 values are significantly increased in the aging group among half of the studied ROIs (57 ROIs out of 134).PMID:37476907 | DOI:10.55730/1300-0144.5630
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Hayriye Akta ş Dinçer Ahmet Muhte şem Ağıldere Didem G ökçay Source Type: research
The effect of different boron compounds on nutrient digestibility, intestinal nutrient transporters, and liver lipid metabolism
This study aimed to determine the effects of different boron (B) derivatives on nutrient digestibility, intestinal nutrient transporters, and lipid metabolism in rats.METHODS: Twenty-one rats were allocated to three groups (n = 7) as follows: (i) Control, (ii) Sodium pentaborate pentahydrate (SPP), and (iii) boric acid (BA). The rats were fed a chow diet (AIN-93M) and supplemented with 8 mg/kg elemental B from SPP (45.2 mg/kg BW) and BA (42.7 mg/kg BW) via oral gavage every other day for 12 weeks. The nutrient digestibility of rats in each group was measured using the indigestible indicator (chromium oxide, Cr2 O3, 0.20%)....
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Emre Şahin Cemal Orhan F üsun Erten Fikrettin Şahin Nurhan Şahin Kazim Şahin Source Type: research
Exosome-mediated long noncoding RNA (lncRNA) PART1 suppresses malignant progression of oral squamous cell carcinoma via miR-17-5p/SOCS6 axis
This study aimed to explore effects of exosome-mediated lncRNA PART1 on OSCC cells.METHODS: This study was performed in Tianjin Medical University Cancer Institute from February 2021 to March 2022. Bioinformatic analysis was performed on the public database GEPIA (http://gepia.cancer-pku.cn/). Exosomes isolated from cell lines squamous cell carcinoma 9 (SCC9) and Centre Antoine Lacassagne-27 (CAL27) were identified by transmission electron microscope and western blot. Exosome-mediated lncRNA PART1, microRNA-17-5p(miR-17-5p) and suppressor of cytokine signaling 6(SOCS6) RNA expressions were assessed by quantitative reverse ...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Yuheng Du Yanjie Shuai Hongling Wang Huisheng Li Yajing Li Source Type: research
Investigation of the value of hematological biomarkers in the clinical differential diagnosis of IgG4-RD
This study aimed to discover new biomarkers that can help for disease diagnosis and its differential diagnosis by reviewing the relationships between neutrophil-lymphocyte ratio (NLR), platelet lymphocyte ratio (PLR), systemic immune-inflammation index (SII), and systemic inflammation response index (SIRI).METHODS: Thirty IgG4- RD, 38 granulomatous polyangiitis (GPA), and 46 sarcoidosis patients presenting to the Rheumatology Clinic meeting the criteria of 2019 American College of Rheumatology, 2012 International Chapel Hill and 1999 American Thoracic Society meeting, respectively, and 27 healthy control subjects were incl...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Hazan Karadeniz Aslihan Avano ğlu Güler R ıza Can Kardaş Muzaffer Karadeniz Hatice Pa şaoğlu Hamit K üçük Berna G öker Abdurrahman Tufan Mehmet Akif Öztürk Source Type: research
Validity and reliability of the Turkish version of the parent perceptions of physical activity scale
DISCUSSION: The Turkish PPPAS, which consists of two subscales, namely the benefits and barriers of physical activity, is valid and reliable. This tool can measure the physical activity perceptions of parents with preschool-age children with neurodevelopmental disorders in the Turkish population.PMID:37476903 | DOI:10.55730/1300-0144.5646
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Kamile Uzun Akkaya M üjde Çalıkuşu İncekar B ülent Elbasan Source Type: research
A national, multicenter, retrospective study evaluating retention rate and efficacy of tocilizumab treatment in patients with active rheumatoid arthritis who had an inadequate response to csDMARDs and/or TNF inhibitors
DISCUSSION: TCZ was found to be effective and safe in RA patients with IR to csDMARDs and/or TNFis. The drug retention rate was considered satisfactory with more than half of the patients continuing TCZ treatment at Month 12.PMID:37476902 | DOI:10.55730/1300-0144.5636
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: G üzide Nevsun İnanç Mustafa Ender Terzio ğlu Yusuf Karabulut Zevcet Y ılmaz Emine Figen Tarhan Mehmet Emin Enecik Ali Şahin Adem K üçük Ay şe Ayan Metin Özgen U ğur Karasu Servet Yolba ş Source Type: research
Investigation of Igf-1, Igf-Bp3 and Igf-Bp5 levels in umbilical cord blood of infants with developmental dysplasia of the hip
DISCUSSION: Umbilical blood samples could potentially help diagnose DDH. The levels of IGF-BP5 were shown to be significantly lower in infants with DDH.PMID:37476901 | DOI:10.55730/1300-0144.5628
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Esra Demirel Ey üp Şenocak Gamze Nur Cimilli Şenocak Ali Şahin Berrin G öktuğ Kadıoğlu Özlem Gündüz Source Type: research
Real-life outcomes for oral disease-modifying treatments of relapsing-remitting multiple sclerosis patients: Adherence and adverse event profiles from Marmara University
This study aims to investigate and compare adherence, adverse event (AE) profiles, and frequencies, main reasons for treatment discontinuation under Teriflunomide (TERI), Dimethyl Fumarate (DMF), and Fingolimod (FNG) for relapsing-remitting MS (RRMS) patients. This study is designed to explore patient-reported experiences in real-life settings.METHODS: Patients who were older than 18 years with a definite diagnosis of RRMS and no history of stem-cell transplantation were included. Outpatient clinic data files at the Neurology Department of Marmara University from June 2012 to June 2019 were examined retrospectively.RESULTS...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Ezgi Vural Esin Engin G ülin Sünter Kadriye A ğan Yıldırım Dilek G ünal Source Type: research
Evaluation of treatment regimens and long-term clinical outcomes in patients with isoniazid-resistant pulmonary tuberculosis: a 5-year follow-up
DISCUSSION: Our study results show higher treatment success and positive results with the treatment regimen containing FQ and that treatment with HREZ for nine months is associated with a lower treatment success rate.PMID:37476899 | DOI:10.55730/1300-0144.5639
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Ay şe Feyza Aslan Mediha G önenç Ortaköylü Belma Akbaba Ba ğcı Sezer Toprak Source Type: research
What is the impact of inflammasome mechanisms on male infertility?
DISCUSSION: Inflammasome mechanisms, such as NLRP3 and IL1-β molecules, may provide additional benefit in evaluating the need and benefit of surgical or medical treatment in infertility with and without vascular pathology and with and without azoospermia.PMID:37476898 | DOI:10.55730/1300-0144.5631
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Eser Ördek B ülent Kati İsmail Koyuncu Mehmet Demir İsmail Yağmur Eyyup Sabri Pelit Halil Çiftçi Ercan Yeni Source Type: research
Can development of asthma and bronchial hyperreactivity be reduced by subcutaneous immunotherapy in adult patients with allergic rhinitis?
In this study, data was recorded for patients with a mite and/or grasses/cereals pollen allergy who were tested for BHR before planned SCIT, and who had allergic rhinitis, with or without asthma. The SCIT group was selected as those who received SCIT for at least one year. The control group was selected from those who were scheduled to receive SCIT but were waived and still receiving medication. Symptom scores, prick test results, PC20 levels (methacholine challenge that is a provocative concentration causing a 20% fall in FEV1), and the presence of asthma were recorded and compared with data from at least one year after t...
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Fatma Merve Tepetam Cihan Örçen Zeynep Ferhan Özşeker Dildar Duman Sema Sara ç Source Type: research
Expression of dual-specificity phosphatases in TGF ß1-induced EMT in SKOV3 cells
DISCUSSION: TGFβ1 induced EMT which was accompanied by increased activity of MAPKs, and led to marked changes in expressions of several DUSPs in SKOV3 cells.PMID:37476896 | DOI:10.55730/1300-0144.5626
Source: Turkish Journal of Medical Sciences - July 21, 2023 Category: General Medicine Authors: Sabire G üler Abdullah Yal çın Source Type: research
