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Total 120 results found since Jan 2013.

Actual Telemedicine Needs of Japanese Patients with Neurological Disorders in the COVID-19 Pandemic
Conclusion We can contribute to the management of the COVID-19 pandemic and the medical economy by promoting telemedicine, especially for young patients with headaches or epilepsy.PMID:36418105 | DOI:10.2169/internalmedicine.9702-22
Source: Internal Medicine - November 23, 2022 Category: Internal Medicine Authors: Ryo Sasaki Taijun Yunoki Yumiko Nakano Yusuke Fukui Mami Takemoto Ryuta Morihara Koji Abe Toru Yamashita Source Type: research

Becker Muscular Dystrophy Accompanied by Anti-HMGCR Antibody-positive Immune-mediated Necrotizing Myopathy
Intern Med. 2022 Sep 21. doi: 10.2169/internalmedicine.0202-22. Online ahead of print.ABSTRACTBecker muscular dystrophy (BMD) is an X-linked neuromuscular disease characterized by progressive muscle weakness that currently has no cure. Immune-mediated necrotizing myopathy (IMNM) is a type of autoimmune inflammatory myopathy characterized by proximal muscle weakness that is treated with immunosuppressive therapy. We herein report a patient diagnosed with BMD complicated with IMNM by a pathological analysis. Notably, the patient had an elevated serum anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase antibody level. Oral g...
Source: Internal Medicine - September 21, 2022 Category: Internal Medicine Authors: Asami Munekane Yutaka Ohsawa Mariko Okubo Taiji Nagai Hirotake Nishimura Ichizo Nishino Yoshihide Sunada Source Type: research

Anti-signal Recognition Particle Antibody-positive Immune-mediated Myopathy after mRNA-1273 SARS-CoV-2 Vaccination
Intern Med. 2022 Sep 13. doi: 10.2169/internalmedicine.0404-22. Online ahead of print.ABSTRACTA 26-year-old Japanese woman developed a fever, myalgia and gait disturbance one day after receiving the second dose of the mRNA-1273 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine. A neurological examination revealed symmetrical weakness and myalgia in proximal lower limbs, and a blood examination showed prominent elevation of creatinine kinase. Magnetic resonance imaging (MRI) revealed a high signal intensity in the thigh muscles on short-tau inversion recovery images, and antibody testing revealed positive...
Source: Internal Medicine - September 14, 2022 Category: Internal Medicine Authors: Masanobu Tanemoto Ryosuke Oda Yuichiro Toyama Hirohiko Shizukawa Kazuki Yokokawa Taro Saito Syuuichirou Suzuki Akihiro Matsumura Shin Hisahara Source Type: research

Inflammatory Myopathy Associated with Anti-mitochondrial Antibody-negative Primary Biliary Cholangitis Diagnosed by a Liver Biopsy: A Case Report
Intern Med. 2022 Aug 10. doi: 10.2169/internalmedicine.9666-22. Online ahead of print.ABSTRACTAnti-mitochondrial antibody (AMA)-associated myopathies represent a homogeneous disease entity with severe arrhythmia and slowly progressive proximal muscle weakness with lordotic posture, irrespective of the presence of primary biliary cholangitis (PBC). We herein report a case of myositis associated with PBC without AMAs. A 48-year-old woman presented with clinical features very similar to AMA-associated myositis, despite negative AMAs. PBC, ascertained by a liver biopsy performed based on mildly elevated liver enzymes, and the ...
Source: Internal Medicine - August 9, 2022 Category: Internal Medicine Authors: Mitsuhiro Kainaga Takuya Sasaki Mizuki Kitamura Takahiro Nakayama Keita Masuda Yukio Kakuta Ichizo Nishino Ichiro Imafuku Source Type: research