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Evaluation of pain-alleviating strategies during allergy shots (subcutaneous immunotherapy): a randomized controlled pilot study
Conclusions. There were no significant differences found between each of the distraction devices and between the control group. Type II error/false negative finding cannot be ruled out because of a small sample. Therefore, we cannot conclude that no true difference exists between each distraction device and the control group simply because of occurrence of a non-significant P-value in our study.PMID:37671862 | DOI:10.23822/EurAnnACI.1764-1489.312
Source: European Annals of Allergy and Clinical Immunology - September 6, 2023 Category: Allergy & Immunology Authors: J Pfieffer K Wehmeier K Gee T DeSanto E Yousef Source Type: research

Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil.
We report a case of anaphylaxis to propofol in an adult patient without food allergy to soy, but with a latent sensitization to soy. An IgE-dependent allergy to propofol was established by a basophil activation test. Here, we document for the first time the existence of specific IgEs to a 65kDa protein, found in soybean oil and soy flour. In the absence of data on the reactogenic threshold for allergenic food proteins injected intravenously, a risk appears to be established and leads us to recommend a systematic detection for proteins in the refined soybean oil used in the pharmaceutical industry for intravenous products. ...
Source: European Annals of Allergy and Clinical Immunology - September 15, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Drug-induced anaphylaxis: seven-year single-center survey.
Conclusions. NSAIDs and antibiotics were responsible for most of DIA. The heterogeneity of mechanisms, the severity of the reactions and the lack of standardized in vivo and/or in vitro tests for some drugs do not allow to confirm the diagnosis in all cases. Patients with DIA should be evaluated in specialized centers to perform accurate diagnosis, to prevent recurrence and to find safe alternatives. PMID: 30028111 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - July 23, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Local anesthetics allergy: who should be tested?
Conclusion. The most common referral reason for testing with LA was a history of DHR to drugs other than LAs, whereas asthma was the third most common referral reason. Patients with a history of multiple DHR may be considered for testing with LAs. Asthmatics and those with other allergic diseases without a history of drug / LA allergy do not need to be tested with LA. PMID: 29384109 [PubMed - as supplied by publisher]
Source: European Annals of Allergy and Clinical Immunology - February 2, 2018 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Pattern of inpatient referrals to a drug allergy unit in Kuwait.
Conclusion. Inpatient drug allergy referrals are highly underreported in Kuwait. PMID: 29249136 [PubMed - in process]
Source: European Annals of Allergy and Clinical Immunology - December 19, 2017 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil.
We report a case of anaphylaxis to propofol in an adult patient without food allergy to soy, but with a latent sensitization to soy. An IgE-dependent allergy to propofol was established by a basophil activation test. Here, we document for the first time the existence of specific IgEs to a 65kDa protein, found in soybean oil and soy flour. In the absence of data on the reactogenic threshold for allergenic food proteins injected intravenously, a risk appears to be established and leads us to recommend a systematic detection for proteins in the refined soybean oil used in the pharmaceutical industry for intravenous products. ...
Source: European Annals of Allergy and Clinical Immunology - May 8, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research

Challenge-proven immediate type multiple local anesthetic hypersensitivity in a child.
Authors: Ertoy Karagol I, Yilmaz O, Bakirtas A Abstract Adverse reactions to local anesthetics (LA) are commonly reported in patients undergoing dental procedures and other minor surgical procedures. Most of these reactions, however, originate from psychosomatic, vasovagal or toxic conditions and are not immune-mediated. True immune-mediated reactions are considered extremely rare and are estimated to account for less than 1% of all adverse reactions to LA. On the other hand, almost all of the immune-mediated LA reactions that have been reported are related to adult patients. Here, however, we will present a pediat...
Source: European Annals of Allergy and Clinical Immunology - January 28, 2016 Category: Allergy & Immunology Tags: Eur Ann Allergy Clin Immunol Source Type: research