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A review and update on the diagnosis and treatment of neuropsychiatric Wilson disease.
Authors: Cleymaet S, Nagayoshi K, Gettings E, Faden J Abstract Introduction: This paper reviews the presenting signs and symptoms of Wilson's disease, with an emphasis on the recognition and treatment of neuropsychiatric symptoms. Areas covered: A literature search was conducted using PubMed.gov utilizing the following keywords: Wilson Disease, neuropsychiatric, psychiatric symptoms, treatment, antipsychotics, mood stabilizer, psychotherapy, antidepressant, ATP7B. The diagnosis of Wilson's disease and the treatment of hepatic and neuropsychiatric symptoms are reviewed. Expert opinion: Wilson's disease is a rare autoso...
Source: Expert Review of Neurotherapeutics - July 19, 2019 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Psilocybin for treating substance use disorders?
Authors: de Veen BT, Schellekens AF, Verheij MM, Homberg JR Abstract INTRODUCTION: Evidence based treatment for Substance use disorders (SUD) includes psychotherapy and pharmacotherapy. However, these are only partially effective. Hallucinogens, such as psilocybin, may represent potential new treatment options for SUD. This review provides a summary of (human) studies on the putative therapeutic effects of psilocybin, and discusses the receptor systems, brain regions and cognitive and emotional processes mediating psilocybin's effects. Psilocybin's chemical structure is similar to that of serotonin. Dysregulations in ...
Source: Expert Review of Neurotherapeutics - September 30, 2016 Category: Neurology Tags: Expert Rev Neurother Source Type: research