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Brain Circuits and Neurochemical Systems in Essential Tremor:Insights into Current and Future Pharmacotherapeutic Approaches.
Authors: Schaefer SM, Vives Rodriguez A, Louis ED Abstract INTRODUCTION: There are few medications that are available for the treatment of essential tremor (ET) and they are only moderately effective. Areas covered: Data were obtained from a PubMed search. Original articles, review articles, and clinical guidelines were included. Two disease models for ET have been proposed: 1) the olivary model, which attributes ET to a pathological pacemaker in the inferior olivary nucleus, and 2) the cerebellar degeneration model, which postulates that ET originates in the cerebellum and could be related to deficient or abnormal Pu...
Source: Expert Review of Neurotherapeutics - December 6, 2017 Category: Neurology Tags: Expert Rev Neurother Source Type: research