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Specialty: Drugs & Pharmacology
Source: Journal of Physiology and Pharmacology
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Total 108 results found since Jan 2013.
The effect of neuropilin-1 silencing on the transforming growth factor- β1-mediated epithelial-mesenchymal transition of colon cancer SW480 cells and its effect on the proliferation and migration of colon cancer cells
In conclusion: silencing, NRP-1 in colon cancer SW480 cells can partially reverse TGF-β1-mediated EMT, reduce the proliferation activity of colon cancer cells, and slow their migration ability. Therefore, NRP-1 may become a new target for the treatment of colon cancer.PMID:36193963 | DOI:10.26402/jpp.2022.2.07
Source: Journal of Physiology and Pharmacology - October 4, 2022 Category: Drugs & Pharmacology Authors: B Zhu Q-Q Zhan Q-Y Liu X Yang Y-H Ge G-Y Ding S Guo W-G Xu Source Type: research
The factors involved in the induction of neutrophil gelatinase-associated lipocalin overexpression in renal tubular epithelial cells under endoplasmic reticulum stress
This study investigated the factors involved when inducing NGAL overexpression in HK-2 cells during ERS. The cells were divided into six groups: the control group (normal HK-2 cells), the ERS group (HK-2 cells cultured in complete medium with thapsigargin (TG)), the transfection group (HK-2 cells transfected with activating transcription factor 4 small interfering ribonucleic acid (ATF4 siRNA), the ERS after transfection group (HK-2 cells transfected with ATF4 siRNA, then cultured in complete medium with TG), the negative control group (HK-2 cells transfected with siRNA-negative contrast), and the dimethyl sulfoxide (DMSO)...
Source: Journal of Physiology and Pharmacology - October 13, 2021 Category: Drugs & Pharmacology Authors: T Fu L Hou Y Du Source Type: research
