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Source: Allergy, Asthma and Immunology Research

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Skin Test Results and Cross-Reactivity Patterns in IgE- and T-Cell-Mediated Allergy to Gadolinium-Based Contrast Agents
Allergy Asthma Immunol Res. 2021 Nov;13(6):933-938. doi: 10.4168/aair.2021.13.6.933.ABSTRACTAllergies to gadolinium-based contrast agents (GBCAs) are rare and manifest usually as an immediate drug hypersensitivity reaction (DHR), compatible with an immunoglobulin E (IgE)-mediated mechanism. Although the molecular structures of GBCA show some similarities and are either linear or macrocyclic, the frequency and pattern of cross-reactivity remain unclear. However, cross-reactivity has been described. The aim of this investigation was to assess cross-reactivity in patients with GBCA allergy based on skin tests and exposure. We...
Source: Allergy, Asthma and Immunology Research - November 4, 2021 Category: Allergy & Immunology Authors: Hans-Peter Grueber Arthur Helbling Lukas Joerg Source Type: research