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Source: European Respiratory Journal

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Total 2423 results found since Jan 2013.

Zinc finger protein 33B demonstrates sex interaction with atopy-related markers in childhood asthma
Conclusions We report SNPs in/near a zinc finger gene as novel sex-differential loci for atopy-related markers with opposite effect directions in females and males. A potential role for ZNF33B should be studied further as an important driver of sex-divergent features of atopy in childhood asthma.
Source: European Respiratory Journal - January 6, 2023 Category: Respiratory Medicine Authors: Lee, S., Prokopenko, D., Kelly, R. S., Lutz, S., Ann Lasky-Su, J., Cho, M. H., Laurie, C., Celedon, J. C., Lange, C., Weiss, S. T., Hecker, J., DeMeo, D. L. Tags: Asthma and allergy Original Articles: Asthma Source Type: research

Preschool children's asthma and allergic symptoms in Chongqing, China, associated with parental health: Reporting bias or shared home environment
Conclusions: Consistent associations between home dampness and children's asthma and allergy were found. Reporting bias could influence prevalence of children's asthma and allergy, and adjustment for parental health can be needed, especially in ecological analysis.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Wang, J., Li, B., Yu, W., Yang, Q., Wang, H., Sundell, J., Norback, D. Tags: 6.2 Occupational and Environmental Health Source Type: research

Occupational rhinitis and contact urticaria caused by palladium salts
Conclusions: To our knowledge, this is the first reported case of occupational allergic rhinitis and contact urticaria caused by palladium salts confirmed by nasal provocation testing and skin prick testing. Although immediate allergy to palladium appears to be rare, it is a possible cause of occupational rhinitis and contact urticaria in workers exposed to palladium salts.References: Daenen M. et al. Occupational asthma caused by palladium. Eur Respir J 1999;13:213-216.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Jungewelter, S., Pesonen, M., Voutilainen, R., Suuronen, K. Tags: 6.2 Occupational and Environmental Health Source Type: research

Associations between fractional exhaled nitric oxide (FeNO), asthma, respiratory symptoms and self-reported allergies in female university students in Kobe, Japan
In conclusion, asthma diagnosis, current respiratory symptoms, especially wheeze, and self-reported allergies can be determinants of increased FeNO in Japanese female students.
Source: European Respiratory Journal - October 30, 2015 Category: Respiratory Medicine Authors: Takaoka, M., Norbäck, D. Tags: 6.1 Epidemiology Source Type: research

Associations between TARC/TSLP with asthma characteristics in adults: the EGEA study
Thymus and Activation Regulated Chemokine (TARC) and Thymic Stromal Lymphopoeitin (TSLP) are involved in the pro-Th2 inflammatory response. To date, there is no epidemiological studies that have simultaneously investigated TARC and TSLP with various asthma characteristics and allergy in adults.We investigated the associations between TARC/TSLP and various asthma and allergic characteristics in the Epidemiological study on the Genetics and Environment of Asthma (EGEA).Cross-sectional analyses were performed at EGEA2 (second survey, 2003-2007). Asthma characteristics were defined by standardized questionnaires and lung funct...
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: IBRAHIM, B., Achour, D., Zerimech, F., De Nadai, P., Siroux, V., Tsicopoulos, A., Matran, R., Granger, V., Nadif, R. Tags: Epidemiology Source Type: research

HBD-2 mutations are associated with childhood asthma and prophylactic hBD-2 application prevents asthma in mice
Conclusions: Variations in hBD-2 coding genes associate with increased asthma and allergy risk, while early hBD-2 administration hinders atopic asthma symptoms in mice. Further research is needed to evaluate if and how hBD-2 is involved in the protective farm effect against asthma and allergy.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Borchers, N., Santos-Valente, E., Toncheva, A. A., Wehkamp, J., Franke, A., Gaertner, V. D., Nordkild, P., Genuneit, J., Jensen, B. A. H., Kabesch, M. Tags: Paediatric lung cell and molecular biology Source Type: research

Distribution of biomarkers in severe asthma and severe uncontrolled asthma
Conclusion: The distribution and overlap of high EOS, high FeNO and history of allergy were similar among NOVELTY patients with severe asthma and the subset of these with severe uncontrolled asthma.
Source: European Respiratory Journal - November 25, 2021 Category: Respiratory Medicine Authors: Ding, B., Chen, S., Agrawal, A., Srivastava, D., Solorzano, J., Cook, B., Papi, A., Reddel, H. K. Tags: Epidemiology Source Type: research

Identification and characterization of maize-specific pollen allergens
Conclusions: There is evidence that maize pollen has a relevant allergenicity. 2 of the 4 maize pollen allergens we found (14-3-3-like proteins and endothelial differentiation-relating factor) belong to protein families which have not been described as allergens before. We conclude that beyond its cross-reactivity to other poaceae maize pollen is also a specific allergen.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Bittner, C., Velasco Garrido, M., Harth, V., Peters, U., Brettschneider, R. Tags: Occupational and Environmental Health Source Type: research

Blood eosinophils and obstructive lung diseases - results from the population-based Austrian LEAD Study
Conclusion: Eos are equally distributed in a normal population. Eosinophilia is associated with allergy and/or atopy and highly prevalent in asthma. In COPD there are no such associations suggesting other inflammatory mechanisms.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Hartl, S., Breyer-Kohansal, R., Breyer, M. K., Urban, M., Studnicka, M., Burghuber, O. C. Tags: Epidemiology Source Type: research

The management of allergic reactions in the pre-hospital setting: Does parenteral adrenaline get used unnecessarily?>
Conclusion: The potentially complex nature of diagnosing anaphylaxis in the pre-hospital setting and need for further development is highlighted by both the administration of adrenaline to non-anaphylactic patients and the delay in administration to those presenting with anaphylaxis.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Mortimer, C. Tags: General Practice and Primary Care Source Type: research

Effect of host and environmental factors on asthma control: AIS LIFE project
Conclusions: allergy control may benefit from residential surrounding green spaces. Supported by EU LIFE program, project no. LIFE13 ENV/IT/001107.
Source: European Respiratory Journal - November 20, 2019 Category: Respiratory Medicine Authors: Baldacci, S., Maio, S., Simoni, M., Angino, A., Silvi, P., La Grutta, S., Viegi, G., Ruggiero, F., Bedini, G., Natali, F., Cecchi, L., Prentovic, M., Berger, U., Moustafa, A., Annesi-Maesano, I., Monnier, S., Thibaudon, M., Orlandini, S. Tags: Epidemiology Source Type: research

EAACI Task Force Logograms: Asthma logogram to facilitate the diagnosis of asthma in primary care
Discussion: Based on existing guidelines, we developed a simple and pragmatic asthma logogram for primary care in order to support GPs in making a (provisional) allergy diagnosis. Further steps will be peer validation and computerization of the logograms.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Kocks, J. W. H., Romberg, K., Flokstra-De Blok, B., Angier, L., Clark, E., Demoly, P., Gaudin, C., Gawlik, R., Mamodaly, M., Tanno, L., Van Der Velde, T., Ryan, D. Tags: General practice and primary care Source Type: research

Foetal exposure to heavy metals and risk of asthma and allergic diseases in early childhood: a population-based birth-cohort study
Conclusions: Our results suggest that prenatal exposure to heavy metals may affect the development of asthma and allergic diseases in childhood.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Pesce, G., Baiz, N., Huel, G., Annesi Maesano, I., On behalf of the EDEN consortium Tags: Occupational and environmental health Source Type: research

Association of asthma genetic variants with asthma-associated traits reveals molecular networks of eosinophilic asthma
Conclusion: Many asthma SNPs are also associated with blood eosinophilia, and genetically driven molecular networks of eosinophilic asthma were identified.
Source: European Respiratory Journal - December 1, 2022 Category: Respiratory Medicine Authors: Elhusseini, Z., Vonk, J., Van Den Berge, M., Gosens, R., Koppelman, G. Tags: 03.01 - Molecular pathology and functional genomics Source Type: research

The 2007-2013 trends in the prevalence of allergic rhinitis and asthma in primary schoolchildren in Budapest
The aim of our study was to assess the changes in the prevalence of allergic rhinitis and allergy in 6-12-year-old schoolchildren in 2007 and 2013 in Budapest.Twocross-sectional surveys according to the ISAAC protocol were carried out in the same 21 randomly selected primary schools in Budapest in 2007 and 2013. A school-based sample of 6335 participants in the 2007 survey and 6441 participants in the 2013 survey was the study population.Results: The response rates in 2007 and 2013 were 62.08% and 52.97% respectively.The physician-diagnosed allergic rhinitis was 11.6% (n=413) in 2007 and 11.1% (n=380) in 2013, so it remain...
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Galffy, G., Hirshberg, A., Katona, G., Sultesz, M. Tags: 6.1 Epidemiology Source Type: research