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Source: The Journal of Allergy and Clinical Immunology: In Practice

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The Use of Telemedicine for Penicillin Allergy Skin Testing
Conclusion Telemedicine is an effective and novel approach to facilitate PST in the inpatient setting and carries a high degree of patient satisfaction. This method has the potential to optimize and improve access to Allergy/Immunology resources.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 11, 2018 Category: Allergy & Immunology Source Type: research

A Retrospective Critical Analysis and Risk Stratification of Penicillin Allergy De-labelling in a UK Specialist Regional Allergy Service
Conclusion Systematic clinical characterisation and risk stratification has an important role in Pen-A de-labelling. These data provide proof of concept for a guideline-based selection of patients labelled with Pen-A for a direct penicillin challenge. Patients in the ‘low risk’ group seem suitable for this intervention, although a rigorous prospective evaluation is needed in a multi-centre study.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 5, 2018 Category: Allergy & Immunology Source Type: research

Drug Rash Eosinophilia and Systemic Symptoms (DRESS) Syndrome Identified in the Electronic Health Record Allergy Module
ConclusionsUsing free text search of the EHR allergy module identified a large US DRESS syndrome cohort. DRESS prevalence was 2.18 per 100,000 patients. Both liver and kidney injury were frequent, and vancomycin was the most common drug culprit. DRESS cases were morbid and resource-intensive.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 1, 2018 Category: Allergy & Immunology Source Type: research

Comparison of Basophil Activation Test and Skin Testing Performances in NMBA Allergy
ConclusionIn our technical conditions, BAT does not replace skin testing in the assessment of NMBA allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 6, 2018 Category: Allergy & Immunology Source Type: research

A Patch Testing Initiative for the Investigation of Allergic Contact Dermatitis in a UK Allergy Practice: A Retrospective Study
ConclusionACD was detected in almost 50% of assessed patients and we highlight the importance of assessing relevance. Hydroperoxides of limonene and linalool are notable additions to the prevalence data. Patch testing should be incorporated into more allergy practices, although availability of training is a limiting factor.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 7, 2018 Category: Allergy & Immunology Source Type: research

Allergen Extracts for In Vivo Diagnosis and Treatment of Allergy: Is There a Future?
Publication date: Available online 5 October 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Rudolf Valenta, Alexander Karaulov, Verena Niederberger, Yury Zhernov, Olga Elisyutina, Raffaela Campana, Margarete Focke-Tejkl, Mirela Curin, Leyla Namazova-Baranova, Jiu-Yao Wang, Ruby Paw.ar, Musa KhaitovToday, in vivo allergy diagnosis and allergen-specific immunotherapy (AIT) are still based on allergen extracts obtained from natural allergen sources. Several studies analyzing the composition of natural allergen extracts have shown severe problems regarding their quality such as the presence ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 6, 2018 Category: Allergy & Immunology Source Type: research

The Use of Telemedicine for Penicillin Allergy Skin Testing
ConclusionsTelemedicine is an effective and novel approach to facilitate PST in the inpatient setting and carries a high degree of patient satisfaction. This method has the potential to optimize and improve access to allergy/immunology resources.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 2, 2018 Category: Allergy & Immunology Source Type: research

Allergen recognition patterns in walnut allergy are age dependent and correlate with the severity of allergic reactions
ConclusionSensitization to walnut storage proteins is acquired in childhood and correlates with severe reactions. sIgE levels to storage proteins Jug_r_1, Jug_r_4 and vicilin fractions, but not to nsLTP and PR-10 proteins, correlate with systemic reactions to walnut.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 30, 2019 Category: Allergy & Immunology Source Type: research

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Identified in the Electronic Health Record Allergy Module
ConclusionsUsing free-text search of the EHR allergy module identified a large US DRESS syndrome cohort. DRESS prevalence was 2.18 per 100,000 patients. Both liver and kidney injury were frequent, and vancomycin was the most common drug culprit. DRESS cases were morbid and resource-intensive.
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2019 Category: Allergy & Immunology Source Type: research

Management of Peanut Allergy
Publication date: February 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 2Author(s): Carina Venter, Scott H. Sicherer, Matthew GreenhawtPeanut allergy is a growing public health concern in westernized countries. Peanut allergy is characterized as an often severe and lifelong allergy, which can have detrimental effects on quality of life and trigger anxiety. Although multiple therapeutic options are emerging, the focus of current management strategies is strict peanut avoidance and carriage of self-injectable epinephrine. The greatest risk of reacting to peanut comes from direct in...
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2019 Category: Allergy & Immunology Source Type: research

Penicillin allergy evaluation: A prospective, multicenter, open label evaluation of a comprehensive penicillin skin test kit
ConclusionThe Penicillin Skin Test Kit, containing all relevant penicillin allergenic determinants, demonstrated very high NPV. Removal of a penicillin allergy label in a large majority of currently mislabeled patients has substantial personal and public health implications.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 14, 2019 Category: Allergy & Immunology Source Type: research

Food allergy in adults: substantial variation in prevalence and causative foods across Europe
ConclusionFood allergy shows substantial geographical variation in prevalence and causative foods across Europe. Although probable FA is less common than self-reported FA, prevalence still reaches 6% in parts of Europe.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 19, 2019 Category: Allergy & Immunology Source Type: research

Patterns of North American Women Authorship in Two Allergy/Immunology Journals: 1997-2017
ConclusionsWomen authorship has become more frequent in JACI and Annals. The probability of women being first authors is more likely in articles with women as last authors- implying that mentorship of women by women may encourage women to become more active in scholarship.
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 5, 2019 Category: Allergy & Immunology Source Type: research

Penicillin Allergy Evaluation: A Prospective, Multicenter, Open-Label Evaluation of a Comprehensive Penicillin Skin Test Kit
ConclusionsThe Penicillin Skin Test Kit, containing all relevant penicillin allergenic determinants, demonstrated very high NPV. Removal of a penicillin allergy label in a large majority of currently mislabeled patients has substantial personal and public health implications.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 3, 2019 Category: Allergy & Immunology Source Type: research