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Source: The Journal of Allergy and Clinical Immunology: In Practice

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Epinephrine Use in Positive Oral Food Challenges Performed as a Screening Test for Food Allergy Therapy Trials
Conclusions Screening OFCs to confirm food allergies can be performed safely, but there was a higher rate of epinephrine use compared with OFCs used for assessing food allergy outgrowth. Therefore, personnel skilled and experienced in the recognition of early signs and symptoms of anaphylaxis who can promptly initiate treatment are required.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 5, 2015 Category: Allergy & Immunology Source Type: research

Molecular Diagnosis of Shrimp Allergy: Efficiency of Several Allergens to Predict Clinical Reactivity
Conclusion Tropomyosin and sarcoplasmic-calcium-binding-protein sensitization is associated with clinical reactivity to shrimp. Myosin light chain testing may help in the diagnosis of clinical reactivity. Arginine kinase and hemocyanin appear to be cross-reacting allergens between shrimp and arthropods. Detection of IgE to these allergens and some of their epitopes may be better diagnostic tools in the routine workup of shrimp allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2015 Category: Allergy & Immunology Source Type: research

Oral Immunotherapy for Egg Allergy: A Double-Blind Placebo-Controlled Study, with Postdesensitization Follow-Up
Conclusion Egg OIT results in desensitization in almost all subjects, although tolerance was maintained in only 1/3 of them after a 3-month period of withdrawal. Side effects were encountered, but the procedure appeared safe. In hen egg allergy, OIT is effective for desensitization.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2015 Category: Allergy & Immunology Source Type: research

Cor a 14, Hazelnut Specific IgE, and SPT as a Reliable Tool in Hazelnut Allergy Diagnosis in Eastern Mediterranean Children
Conclusion Cor a 14 was found to be a useful and reliable tool for predicting clinical reactivity in children with hazelnut allergy in the Eastern Mediterranean area.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 5, 2016 Category: Allergy & Immunology Source Type: research

Clinical Management of Psychosocial Concerns Related to Food Allergy
Publication date: March–April 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 2 Author(s): Linda Herbert, Eyal Shemesh, Bruce Bender Current estimates indicate that 4% to 8% of children in the United States are diagnosed with food allergy, and more than 40% of US children with food allergy experience severe allergic reactions. Families trying to avoid foods that may trigger an allergic reaction and ensure adequate treatment of allergic reactions that do occur face numerous challenges. The rise in the number of children diagnosed with food allergies underscores the importance ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 8, 2016 Category: Allergy & Immunology Source Type: research

Cor a 14, Hazelnut-Specific IgE, and SPT as a Reliable Tool in Hazelnut Allergy Diagnosis in Eastern Mediterranean Children
Conclusion Cor a 14 was found to be a useful and reliable tool for predicting clinical reactivity in children with hazelnut allergy in the Eastern Mediterranean area.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 8, 2016 Category: Allergy & Immunology Source Type: research

Updating Allergy and/or Hypersensitivity Diagnostic Procedures in the WHO ICD-11 Revision
Publication date: July–August 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 4 Author(s): Luciana Kase Tanno, Moises A. Calderon, James Li, Thomas Casale, Pascal Demoly The classification of allergy and/or hypersensitivity conditions for the World Health Organization (WHO) International Classification of Diseases (ICD)-11 provides the appropriate corresponding codes for allergic diseases, assuming that the final diagnosis is correct. This classification should be linked to in vitro and in vivo diagnostic procedures. Considering the impact for our specialty, we decided to...
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 6, 2016 Category: Allergy & Immunology Source Type: research

Threshold Dose Distribution in Walnut Allergy
Conclusions Our data indicate that population EDs for walnut are slightly higher compared with those for peanut and hazelnut allergy. Currently available data indicate that the ED values for hazelnut could be used as a conservative temporary placeholder when implementing risk management strategies for other tree nuts where little or no food challenge data are available.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 18, 2017 Category: Allergy & Immunology Source Type: research

Food Allergy –Related Risk-Taking and Management Behaviors Among Adolescents and Young Adults
Conclusions Among AYA, increased FA-related risk-taking was associated with clinical, demographic, and social factors, including peanut allergy, greater age, as well as absence of social support and specific school FA policies. These associations may be used to inform future interventions designed to address FA-related risk and management behaviors.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 27, 2017 Category: Allergy & Immunology Source Type: research

The Journal of Allergy and Clinical Immunology: In Practice — 2016 Year in Review
Publication date: Available online 28 January 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Michael Schatz, Scott H. Sicherer, Robert S. Zeiger As editors, we concluded that it would be helpful to our readers to write a Year in Review article that highlights the Review, Original, and Clinical Communication articles published in 2016 in The Journal of Allergy and Clinical Immunology: In Practice. We summarized articles on the topics of asthma, rhinitis/rhinosinusitis, food allergy, anaphylaxis, drug allergy, urticarial/angioedema, eosinophilic disorders, and immunodeficiency. Within eac...
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 28, 2017 Category: Allergy & Immunology Source Type: research

Positive Skin Test or Specific IgE to Penicillin Does Not Reliably Predict Penicillin Allergy
Conclusions The best predictor for a clinically significant (IgE-mediated) penicillin allergy is a combination of a positive case history with simultaneous positive ST result and s-IgE or a positive challenge result.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 5, 2017 Category: Allergy & Immunology Source Type: research

The Utility of the Reflux Symptom Index for Diagnosis of Laryngopharyngeal Reflux in an Allergy Patient Population
Conclusions An RSI score of 19 appears to represent the best threshold for predicting LPR in an allergy clinic patient population.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 9, 2017 Category: Allergy & Immunology Source Type: research

Current Status and Unanswered Questions for Food Allergy Treatments
Publication date: Available online 20 November 2017 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Rima Rachid, Corinne A. Keet Although there is no FDA approved therapy for food allergy, over the past decades, several routes of immunotherapy have been investigated for food allergy. Thus far, these therapies have shown variable levels of efficacy at desensitizing to foods, with oral immunotherapy (OIT) far more successful than sublingual immunotherapy (SLIT) or epicutaneous immunotherapy (EPIT). However, desensitization tends to be temporary, and safety remains a major concern with OIT. More...
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research

The Allergist's Role in Anaphylaxis and Food Allergy Management in the School and Childcare Setting
We present the current evidence base, suggest resources, and highlight areas of current controversy that warrant further study.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 17, 2017 Category: Allergy & Immunology Source Type: research

Preliminary Development of the Food Allergy Coping and Emotions Questionnaires for Children, Adolescents, and Young People: Qualitative Analysis of Data on IgE-Mediated Food Allergy from Five Countries
Conclusions Early-life experiences provide the foundation for later cognitions and behaviors. The expanded FACE developmental model is useful in explaining emotions and coping styles across different age groups and countries. These data will also be used to generate an age-specific bank of items for the development of 3 (age-specific self-report, and parent proxy) questionnaires to assess emotions and coping in food allergy. Findings provide insight into how particular styles of coping develop and vary from patient to patient and may also guide clinician-patient communication and the development of individualized management strategies.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 7, 2018 Category: Allergy & Immunology Source Type: research