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Source: The Journal of Allergy and Clinical Immunology: In Practice

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Quality of Life in Patients with Allergic Reactions to Medications: Influence of a Drug Allergy Evaluation
ConclusionsHaving suffered anaphylaxis, more than 1 reported drug allergy or presenting a musculoskeletal disease are factors that worsen the quality of life. Quality of life improved significantly after completing a drug allergy evaluation.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 20, 2019 Category: Allergy & Immunology Source Type: research

Timing of Introduction, Sensitization and Allergy to Highly-Allergenic Foods at Age 3 Years in a General-Population Canadian Cohort
ConclusionsGeneral-population infants introduced to peanut after age 12 months were more likely to have sensitization and probable clinical allergy to peanut at 3 years.
Source: The Journal of Allergy and Clinical Immunology: In Practice - October 31, 2019 Category: Allergy & Immunology Source Type: research

Camp Leadership Perspectives on Food Allergy Related Anaphylaxis Events and Training for Camp Staff: A National Survey of Summer Camps
ConclusionPresence of appropriate policies to manage food anaphylaxis events and anaphylaxis management training were missing in a substantial proportion of camps. Camp-tailored food allergy training is needed given the number of camps reporting food allergy reactions requiring epinephrine.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 24, 2019 Category: Allergy & Immunology Source Type: research

Timing of Introduction, Sensitization, and Allergy to Highly Allergenic Foods at Age 3 Years in a General-Population Canadian Cohort
ConclusionsGeneral-population infants introduced to peanut after age 12 months were more likely to have sensitization and probable clinical allergy to peanut at 3 years.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 16, 2020 Category: Allergy & Immunology Source Type: research

IgE to Poppy Seed and Morphine Are Not Useful Tools to Diagnose Opiate Allergy
Conclusion Positive sIgE results to poppy seed and morphine are not per se predictive for genuine opiate allergy and should not be used in isolation to diagnose morphine or codeine allergy. To avoid overdiagnosis, for the time being, we propose to supplement serological diagnosis with an oral provocation test. Whether BAT might help to discriminate between clinical reactivity and sensitization remains to be confirmed in larger collaborative studies.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 23, 2015 Category: Allergy & Immunology Source Type: research

The Natural History of Food Allergy
Publication date: March–April 2016 Source:The Journal of Allergy and Clinical Immunology: In Practice, Volume 4, Issue 2 Author(s): Jessica Savage, Scott Sicherer, Robert Wood On a population level, it is well recognized that some IgE-mediated childhood food allergies, such as milk and egg allergies, are more likely to resolve than others, such as peanut and tree nuts allergies. Unfortunately, some studies suggest that resolution rates may have slowed compared with impressions from past decades. The clinician can apply the knowledge of the epidemiology of these allergies to describe likely patient outcomes, and dire...
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 8, 2016 Category: Allergy & Immunology Source Type: research

A Proactive Approach to Penicillin Allergy Testing in Hospitalized Patients
Conclusions Penicillin allergy testing using a physician-pharmacist team model effectively removes reported allergies in hospitalized patients. The electronic medical record is a valuable asset for locating and stratifying individuals who benefit most from intervention. Proactive testing substantially reduces unnecessary inpatient and outpatient use of beta-lactam alternatives that may otherwise go unaddressed.
Source: The Journal of Allergy and Clinical Immunology: In Practice - November 22, 2016 Category: Allergy & Immunology Source Type: research

Role of the Allergist-Immunologist and Upper Airway Allergy in Sleep-Disordered Breathing
Conclusions Clinical allergy practice and the medical literature support a proactive role for allergists in the diagnosis and management of sleep-disordered breathing.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 4, 2016 Category: Allergy & Immunology Source Type: research

Use of a Penicillin Allergy Screening Algorithm and Penicillin Skin Testing for Transitioning Hospitalized Patients to First-Line Antibiotic Therapy
Conclusions The use of the PAHA and subsequent PST is a safe, effective multidisciplinary intervention that facilitates the transition to β-lactam antibiotics. Our approach is unique in that it prioritizes patients based on the use of second-line antibiotics, and then applies an algorithm to determine eligibility for PST.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research

Natural History of Benign Nonimmediate Allergy to Beta-Lactams in Children: A Prospective Study in Retreated Patients After a Positive and a Negative Provocation Test
Conclusions Our data strongly suggest that a fuDPT is safe and useful to assess tolerance acquisition in children with a confirmed benign nonimmediate BL allergy. In addition, our results support the use of a short DPT protocol (2 days), which led to a high NPV of 96.7% in our population, with a favorable benefit-risk balance.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research

Should Younger Siblings of Peanut Allergic Children Be Screened for Peanut Allergy?
Publication date: Available online 1 February 2018 Source:The Journal of Allergy and Clinical Immunology: In Practice Author(s): Elissa M. Abrams, Edmond S. Chan, Scott H. Sicherer The role of screening younger siblings of peanut allergic children with allergy testing before peanut introduction is controversial. Although certain guidelines note some value in screening this population, it is not a direct indication in the recent National Institute of Allergy and Infectious Diseases guideline. Some studies suggest that siblings of peanut allergic children are at increased risk of peanut allergy, whereas others note that del...
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 2, 2018 Category: Allergy & Immunology Source Type: research

Comparison of Basophil Activation Test and Skin Testing Performances in NMBA Allergy
Conclusion In our technical conditions, BAT does not replace skin testing in the assessment of NMBA allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 22, 2018 Category: Allergy & Immunology Source Type: research

Use of a Penicillin Allergy Screening Algorithm and Penicillin Skin Testing for Transitioning Hospitalized Patients to First-Line Antibiotic Therapy
ConclusionsThe use of the PAHA and subsequent PST is a safe, effective multidisciplinary intervention that facilitates the transition to β-lactam antibiotics. Our approach is unique in that it prioritizes patients based on the use of second-line antibiotics, and then applies an algorithm to determine eligibility for PST.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 5, 2018 Category: Allergy & Immunology Source Type: research

Natural History of Benign Nonimmediate Allergy to Beta-Lactams in Children: A Prospective Study in Retreated Patients After a Positive and a Negative Provocation Test
ConclusionsOur data strongly suggest that a fuDPT is safe and useful to assess tolerance acquisition in children with a confirmed benign nonimmediate BL allergy. In addition, our results support the use of a short DPT protocol (2 days), which led to a high NPV of 96.7% in our population, with a favorable benefit-risk balance.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 5, 2018 Category: Allergy & Immunology Source Type: research

Use of a Penicillin Allergy Screening Algorithm and Penicillin Skin Testing for Transitioning Hospitalized Patients to First-Line Antibiotic Therapy
ConclusionsThe use of the PAHA and subsequent PST is a safe, effective multidisciplinary intervention that facilitates the transition to β-lactam antibiotics. Our approach is unique in that it prioritizes patients based on the use of second-line antibiotics, and then applies an algorithm to determine eligibility for PST.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 10, 2018 Category: Allergy & Immunology Source Type: research