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Source: The Journal of Allergy and Clinical Immunology: In Practice

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Risk Factors for Hen’s Egg Allergy in Europe: EuroPrevall birth cohort
ConclusionsSimilar to peanut allergy, eczema was strongly associated with egg allergy development and the association increased with increasing eczema severity. The age of introduction of dietary egg was not a risk factor. The potential role of antibiotics in early life as a risk factor for egg allergy needs further examination.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 15, 2019 Category: Allergy & Immunology Source Type: research

Risk Factors for Hen's Egg Allergy in Europe: EuroPrevall Birth Cohort
ConclusionsSimilar to peanut allergy, eczema was strongly associated with egg allergy development and the association increased with increasing eczema severity. The age of introduction of dietary egg was not a risk factor. The potential role of antibiotics in early life as a risk factor for egg allergy needs further examination.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 29, 2019 Category: Allergy & Immunology Source Type: research

An Australian Consensus on Infant Feeding Guidelines to Prevent Food Allergy: Outcomes From the Australian Infant Feeding Summit
Conclusions Consensus was achieved in a context in which there is a high prevalence of food allergy. Guidelines for other countries are being updated. Provision of consistent wording related to infant feeding to reduce food allergy risk will ensure clear consumer advice.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 10, 2017 Category: Allergy & Immunology Source Type: research

Long Term Follow up after Penicillin Allergy De-labeling in Ambulatory Patients
Conclusion Penicillin allergy annulling via OCT has proven to be effective. Most of the patients who previously avoided penicillins have re-used penicillins safely.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 23, 2018 Category: Allergy & Immunology Source Type: research

Long-Term Follow-Up After Penicillin Allergy Delabeling in Ambulatory Patients
Conclusions Penicillin allergy annulling via OCT has proven to be effective. Most of the patients who previously avoided penicillins have reused penicillins safely.
Source: The Journal of Allergy and Clinical Immunology: In Practice - June 14, 2018 Category: Allergy & Immunology Source Type: research

Antibiotic allergy labels in children are associated with adverse clinical outcomes
ConclusionsThis is the first study demonstrating the negative impact of antibiotic allergy labels on clinical outcomes in children, as evidenced by significant alternate antibiotic use and longer hospital lengths of stay.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 21, 2018 Category: Allergy & Immunology Source Type: research

Controversies in Drug Allergy: Drug Allergy Pathways
We describe the key patient and institutional factors that must be considered in risk stratification, the central feature of pathway design. We detail shared obstacles to widespread beta-lactam allergy pathway implementation and identify potential solutions to address these challenges.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 17, 2018 Category: Allergy & Immunology Source Type: research

Long-Term Follow-Up After Penicillin Allergy Delabeling in Ambulatory Patients
ConclusionsPenicillin allergy annulling via OCT has proven to be effective. Most of the patients who previously avoided penicillins have reused penicillins safely.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 29, 2018 Category: Allergy & Immunology Source Type: research

Patient and primary care physician perceptions of penicillin allergy testing and subsequent use of penicillin containing antibiotics: A qualitative study
ConclusionsClinicians would benefit from information about penicillin allergy testing in order to be able to use these services appropriately, and to discuss referral with patients. Patients might be more motivated to seek testing if they were more informed regarding its benefits. Good communication between primary and secondary care would facilitate the updating of medical records, and promote better patient education.
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 14, 2019 Category: Allergy & Immunology Source Type: research

Radiocontrast media hypersensitivity: skin testing differentiates allergy from non-allergic reactions and identifies a safe alternative as proven by intravenous provocation
ConclusionsThe diagnostic sensitivity of intradermal RCM testing to identify allergic patients is high in both, immediate-type and delayed-type RCM allergy. Intravenous provocation with a skin test-negative RCM is safe and enables identification of a tolerated alternative RCM. Additional skin testing of iodine solution is required to identify patients with iodine allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - April 12, 2019 Category: Allergy & Immunology Source Type: research

Radiocontrast Media Hypersensitivity: Skin Testing Differentiates Allergy From Nonallergic Reactions and Identifies a Safe Alternative as Proven by Intravenous Provocation
ConclusionsThe diagnostic sensitivity of intradermal RCM testing to identify allergic patients is high in both immediate-type and delayed-type RCM allergy. Intravenous provocation with a skin test–negative RCM is safe and enables identification of a tolerated alternative RCM. Additional skin testing of iodine solution is required to identify patients with iodine allergy.
Source: The Journal of Allergy and Clinical Immunology: In Practice - May 9, 2019 Category: Allergy & Immunology Source Type: research

The Prevalence of Eosinophilic Esophagitis in Pediatric Patients with IgE-Mediated Food Allergy
Conclusions Our findings support a clinical association between these conditions that has implications for the management of children with food allergy, and particular relevance to patients undergoing OIT.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 29, 2016 Category: Allergy & Immunology Source Type: research

Low Food Allergy Prevalence Despite Delayed Introduction of Allergenic Foods —Data from the GUSTO Cohort
Conclusions Food allergy rates in Singapore are low despite delayed introduction of allergenic foods. Early introduction of allergenic foods may thus not be necessary in populations in which overall food allergy prevalence is low, and thus infant feeding recommendations should be carefully tailored to individual populations.
Source: The Journal of Allergy and Clinical Immunology: In Practice - July 19, 2017 Category: Allergy & Immunology Source Type: research

The Cost of Penicillin Allergy Evaluation
Conclusions Using TDABC, penicillin allergy evaluation costs $220; even with varied assumptions adjusting for operational challenges, clinical setting, and expanded testing, penicillin allergy evaluation still costs only about $540. This modest investment may be offset for patients treated with costly alternative antibiotics that also may result in adverse consequences.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 22, 2017 Category: Allergy & Immunology Source Type: research

Asthma, Family History of Drug Allergy, and Age Predict Amoxicillin Allergy in Children
Conclusions Skin prick test did not contribute to the diagnosis of amoxicillin allergy. The presence of asthma, family history of drug allergy, and older age at reaction can be used as predictive factors for true amoxicillin allergy in children.
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 16, 2017 Category: Allergy & Immunology Source Type: research